Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.53 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.53 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976239 | 0.98 | CYP1A2 (0.60) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL11093962 | 0.93 | LMNA (0.60) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL13199362 | 0.86 | LMNA (0.63) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL591921 | 0.82 | LMNA (0.51) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL10337895 | 0.82 | TK1 (0.65) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL6883307 | 0.82 | TK1 (0.65) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL18226895 | 0.82 | TK1 (0.65) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL6890252 | 0.82 | TK1 (0.65) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL11397970 | 0.82 | SMN1; SMN2 (0.51) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 | |
| SCHEMBL11034809 | 0.81 | LMNA (0.48) | CYP1A2KMT2ACYP2C19CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1625602-A | Method for selecting drug sensitivity decision factor and method for predetermining drug sensitivity using the selected factor | HOFFMANN LA ROCHE (CH) | 2005-06-08 | — | — | CN | disclosed |
| US-6720337-B2 | Pharmaceutical composition having enhanced antitumor activity and/or reduced side effects, containing an antitumor agent and an hydroxlmic acid derivative | N-GENE RESEARCH LABORATORIES, INC. | 2004-04-13 | — | — | US | disclosed |
| US-6440998-B1 | Pharmaceutical composition having enhanced antitumor activity and/or reduced side effects, containing an antitumor agent and an hydroximic acid derivative | N-GENE RESEARCH LABORATORIES, INC. | 2002-08-27 | — | — | US | disclosed |