Enfenamic Acid

Enfenamic Acid

SCHEMBL10935569

O=C(O)c1ccccc1NCCc1ccccc1.[NaH]

nearest known ligand 0.66

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 3/20 0.66
KDM4C Q9H3R0 3/20 0.66
ALDH1A1 P00352 4/20 0.65
HSD17B10 Q99714 3/20 0.65
HPGD P15428 2/20 0.65
MAPT P10636 2/20 0.59
KDM4E B2RXH2 5/20 0.58
ASPH Q12797 4/20 0.58
KDM8 Q8N371 4/20 0.58
RIOX2 Q8IUF8 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.55
POLB P06746 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
AGTR1 P30556 1/20 0.54
RAB9A P51151 1/20 0.54
PLK1 P53350 1/20 0.54
RXFP1 Q9HBX9 1/20 0.52
CFD P00746 1/20 0.51
ABCC1 P33527 1/20 0.50
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Enfenamic Acid SCHEMBL25191 0.98 KDM6B (0.68) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL28655011 0.89 KDM6B (0.57) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL1116005 0.89 ALDH1A1 (0.72) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL4897624 0.88 KDM6B (0.69) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL13199682 0.87 KDM6B (0.70) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL11499132 0.85 KDM6B (0.68) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL8689214 0.85 ALDH1A1 (0.79) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL5387032 0.85 SIRT2 (0.63) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL12608931 0.85 RXFP1 (0.54) KDM6BKDM4CALDH1A1HSD17B10HPGD
SCHEMBL27823112 0.84 RXFP1 (0.60) KDM6BKDM4CALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0071682-B1 NEW ANTHRANILIC ACID ESTERS HAVING ANTI-INFLAMMATORY ACTIVITY AND THEIR PREPARATION Council of Scientific and Industrial Research (IN) 1985-11-13 EP disclosed
EP-0071682-A1 New anthranilic acid esters having anti-inflammatory activity and their preparation Council of Scientific and Industrial Research (IN) 1983-02-16 EP disclosed
US-4354033-A Anthranilic acid esters COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1982-10-12 US disclosed