Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063465 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL22263746 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL14309197 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL10447558 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL415514 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL3900802 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL8402102 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL13201235 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16195634 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL24183422 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772341-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2010-08-10 | — | — | US | disclosed |
| US-7728090-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2010-06-01 | — | — | US | disclosed |
| US-20100087659-A1 | NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES | LIAW DER-JANG | 2010-04-08 | — | — | US | disclosed |
| US-7323518-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-01-29 | — | — | US | disclosed |
| US-7309751-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-12-18 | — | — | US | disclosed |
| US-7271223-B2 | Norbomene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-7271230-B2 | Norbornene compounds with cross-linkable groups and their derivatives | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-20070073018-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070073079-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070073080-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070073017-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-29 | — | — | US | disclosed |
| US-20070066774-A1 | Norbornene compounds with cross-linkable groups and their derivatives | LIAW DER-JANG | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073080-A1 | Norbornene compounds with cross-linkable groups and their derivatives | OXER1, SQLE, ALOX12 | KDM4E 3761/4885ALDH1A1 638/4885MEN1 1568/4885 |
| US-20070073079-A1 | Norbornene compounds with cross-linkable groups and their derivatives | OXER1, SQLE, ALOX12 | KDM4E 3761/4885ALDH1A1 638/4885MEN1 1568/4885 |
| US-20100087659-A1 | NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES | SQLE, OXER1, MACF1 | KDM4E 3982/4885ALDH1A1 476/4885MEN1 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.