Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10224643 | 0.83 | MTNR1A (0.62) | MTNR1AKEAP1NFE2L2MTNR1BHTR5A | |
| SCHEMBL8435916 | 0.74 | KEAP1 (0.64) | MTNR1AKEAP1NFE2L2MTNR1B | |
| SCHEMBL8884003 | 0.74 | MTNR1A (0.56) | MTNR1AKEAP1NFE2L2MTNR1BHTR5A | |
| SCHEMBL10266973 | 0.73 | CA2 (0.60) | MTNR1AKEAP1NFE2L2CYP2A6CA2 | |
| SCHEMBL8605628 | 0.73 | MTNR1A (0.59) | MTNR1AKEAP1NFE2L2MTNR1BHTR5A | |
| SCHEMBL8605002 | 0.73 | MTNR1A (0.55) | MTNR1AKEAP1NFE2L2MTNR1B | |
| SCHEMBL21887498 | 0.71 | MTNR1A (0.43) | MTNR1AKEAP1NFE2L2MTNR1BCYP2A6 | |
| SCHEMBL6003503 | 0.71 | MTNR1A (0.60) | MTNR1AKEAP1NFE2L2MTNR1BCYP2A6 | |
| SCHEMBL156931 | 0.71 | CYP2A6 (0.69) | MTNR1AKEAP1NFE2L2CYP2A6CA2 | |
| SCHEMBL12820174 | 0.71 | MTNR1A (0.43) | MTNR1AKEAP1NFE2L2MTNR1BCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |