Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.42 |
| ▸ | TNF | P01375 | 15/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201500 | 0.87 | ADAM17 (0.41) | ADAM17TNFDRD2DRD4 | |
| SCHEMBL13201393 | 0.79 | TNF (0.42) | ADAM17TNF | |
| SCHEMBL13201491 | 0.79 | TNF (0.55) | ADAM17TNFDRD2DRD4 | |
| SCHEMBL13201492 | 0.78 | DRD2 (0.41) | ADAM17TNFDRD2DRD4 | |
| SCHEMBL13201493 | 0.77 | DRD2 (0.43) | ADAM17TNFDRD2DRD4 | |
| SCHEMBL13889347 | 0.77 | ADAM17 (0.68) | ADAM17TNF | |
| SCHEMBL13201487 | 0.74 | TNF (0.48) | ADAM17TNF | |
| SCHEMBL13201489 | 0.73 | AOC3 (0.40) | — | |
| SCHEMBL8227926 | 0.72 | AOC3 (0.44) | — | |
| SCHEMBL13218583 | 0.72 | DRD2 (0.41) | ADAM17TNFHDAC1HDAC6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772263-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090156586-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156586-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | ADAMTS1, ADAMTS13, ADAMTS7 | ADAM17 13/4885TNF 5/4885HDAC1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.