SCHEMBL1320182

SCHEMBL1320182

COc1c2cc(C([NH])=O)c(-c3cccc4c3C=C(C)C4)c1CC2

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
DRD2 P14416 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318309 0.86
SCHEMBL1322155 0.84
SCHEMBL1322191 0.84
SCHEMBL1319158 0.83 MAPT (0.32) MAPTDRD2
SCHEMBL1321353 0.82 RAB9A (0.30)
SCHEMBL1318187 0.78
SCHEMBL1322453 0.76
SCHEMBL1319286 0.74 NPC1 (0.33)
SCHEMBL1321050 0.74 NPC1 (0.30)
SCHEMBL1321643 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2368896-B1 Mono-indenyl transition metal compounds and polymerization therewith EXXONMOBIL CHEM PATENTS INC (US) 2016-08-24 EP disclosed
US-8058461-B2 Mono-indenyl transition metal compounds and polymerization therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-11-15 US disclosed
EP-2368896-A1 Mono-indenyl transition metal compounds and polymerization therewith ExxonMobil Chemical Patents Inc. (US) 2011-09-28 EP disclosed
US-20110213109-A1 Mono-Indenyl Transition Metal Compounds and Polymerization Therewith EXXONMOBIL CHEMICAL PATENTS INC. 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110213109-A1 Mono-Indenyl Transition Metal Compounds and Polymerization Therewith ICMT, TERT, PIN1 MAPT 103/4885DRD2 3458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.