Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941820 | 0.84 | NPC1 (0.49) | HSD11B1PDE10APDE2AMBNL1NPC1 | |
| SCHEMBL24407519 | 0.79 | GAA (0.40) | HSD11B1PDE10APDE2AGAAPOLB | |
| SCHEMBL10939886 | 0.77 | HSD11B1 (0.46) | HSD11B1PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31381570 | 0.76 | POLB (0.42) | ADRA1ASMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL12776147 | 0.76 | GRM2 (0.38) | HSD11B1PDE10APDE2ATDP1NPC1 | |
| SCHEMBL9829686 | 0.75 | HSD11B1 (0.50) | HSD11B1TDP1NPC1RAB9APTGS2 | |
| SCHEMBL24409852 | 0.74 | HDAC6 (0.37) | ADRA1APDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10939995 | 0.73 | NPC1 (0.41) | HSD11B1MBNL1NPC1RAB9AGAA | |
| SCHEMBL7297002 | 0.73 | TDP1 (0.45) | HSD11B1PDE10APDE2ATDP1ALDH1A1 | |
| SCHEMBL679761 | 0.72 | NR1H3 (0.68) | NPC1RAB9AHSD17B10NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968091-B2 | Selective herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-9968091-B2 | Selective herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20130237418-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2013-09-12 | — | — | US | disclosed |
| US-20130237418-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2013-09-12 | — | — | US | disclosed |
| US-7776791-B2 | N-heterocyclyl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7776791-B2 | N-heterocyclyl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237418-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | TARS2, TST, TARS1 | ADRA1A 3325/4885HSD11B1 3180/4885PDE10A 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.