SCHEMBL1320439

SCHEMBL1320439

CCCCCCCCCCCC(CCCCCCCCCCC)OC(CCCCCCCCCCC)CCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.47
▸ THRB P10828 1/20 0.47
▸ LMNA P02545 1/20 0.46
▸ DNM1 Q05193 2/20 0.46
▸ OPRM1 P35372 1/20 0.43
▸ SMPD1 P17405 3/20 0.41
▸ GPR84 Q9NQS5 3/20 0.41
▸ FDPS P14324 3/20 0.41
▸ SPHK1 Q9NYA1 1/20 0.41
▸ FFAR1 O14842 1/20 0.41
▸ ZDHHC7 Q9NXF8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312839 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL1932599 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL1318828 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL3793621 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL3795488 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL1311334 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL1931400 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL3799758 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL1932997 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1
SCHEMBL8519807 1.00 TSHR (0.47) TSHRTHRBLMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11628131-B2 Ammonia-free bleaching kit for gentle brightening of keratinous fibers HENKEL AG & CO. KGAA (DE) 2023-04-18 — — US claimed
US-20210169762-A1 AMMONIA-FREE BLEACHING KIT FOR GENTLE BRIGHTENING OF KERATINOUS FIBERS HENKEL AG & CO. KGAA (DE) 2021-06-10 — — US claimed
US-20210169755-A1 DUST REDUCED AMMONIUM FREE BLONDING POWDER HENKEL AG & CO. KGAA (DE) 2021-06-10 — — US claimed
EP-4683610-A1 CATECHOL DERIVATIVES FOR TREATMENT OF SIGNS OF HAIR AGING AND/OR SCALP AGING Henkel AG & Co. KGaA (DE) 2026-01-28 — — EP disclosed
EP-4673228-A1 GEL HAVING IMPROVED USAGE PROPERTIES, FOR OXIDATIVELY CHANGING THE COLOR OF KERATIN FIBERS Henkel AG & Co. KGaA (DE) 2026-01-07 — — EP disclosed
EP-4514306-A1 OXIDATIVE HAIR-LIGHTENING AGENTS HAVING IMPROVED APPLICATION PROPERTIES FOR BLEACHING HAIR ROOTS Henkel AG & Co. KGaA (DE) 2025-03-05 — — EP disclosed
EP-4504133-A1 ANTIDANDRUFF SHAMPOO Henkel AG & Co. KGaA (DE) 2025-02-12 — — EP disclosed
EP-4504135-A1 HAIR TREATMENT COMPOSITIONS HAVING ANTIDANDRUFF ACTION Henkel AG & Co. KGaA (DE) 2025-02-12 — — EP disclosed
EP-4475813-A1 OXIDATIVE HAIR TREATMENT AGENT WITH A CONTROLLED HEAT DEVELOPMENT BASED ON ENVIRONMENTALLY FRIENDLY CONTENTS Henkel AG & Co. KGaA (DE) 2024-12-18 — — EP disclosed
EP-3082959-B2 COSMETIC HAIR CLEANSING COMPOSITION HENKEL AG & CO KGAA (DE) 2024-12-04 — — EP disclosed
EP-4469017-A1 PROCESS FOR TREATING KERATINOUS MATERIAL, COMPRISING THE MIXING OF AT LEAST TWO AGENTS (A) AND (B) Henkel AG & Co. KGaA (DE) 2024-12-04 — — EP disclosed
US-20050039271-A1 Colouring agents HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2005-02-24 — — US disclosed
WO-2005013931-A1 USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-17 — — WO disclosed
US-20040208837-A1 Agents and method for treating keratinous fibers KRUEGER MARCUS (DE) 2004-10-21 — — US disclosed
US-6730290-B2 MIXTURE CONTAINING WAX, EMULSIFIERS AND PROPELLANTS HANS SCHWARZKOPF GMBH & CO. KG (DE) 2004-05-04 — — US disclosed
US-20040064901-A1 Enzymatic coloring agents HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-04-08 — — US disclosed
EP-1378231-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles Ciba Specialty Chemicals Holding Inc. (CH) 2004-01-07 — — EP disclosed
US-20030235540-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CIBA SPECIALTY CHEMICALS CORP. 2003-12-25 — — US disclosed
US-6648925-B1 Including clathrate compounds having organometalic complex containing cavities HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-11-18 — — US disclosed
US-20030118516-A1 Aerosol spray HENKEL AG & CO. KGAA (DE) 2003-06-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050039271-A1 Colouring agents KRT18, CKMT1A; CKMT1B, CUTA TSHR 4042/4885THRB 4443/4885LMNA 198/4885
US-20030235540-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CUTA, LIPC, AUP1 TSHR 3689/4885THRB 4567/4885LMNA 770/4885
US-20040064901-A1 Enzymatic coloring agents GLA, HEXA, HSD17B14 TSHR 4375/4885THRB 4456/4885LMNA 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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