Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626004 | 0.85 | MAPT (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL158168 | 0.85 | MAPT (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL43843 | 0.85 | MAPT (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL5283079 | 0.79 | USP2 (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL5324038 | 0.79 | USP2 (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL2971633 | 0.78 | GRIA1 (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL2971635 | 0.78 | GRIA1 (0.47) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL5282915 | 0.78 | USP2 (0.46) | TSHRCYP2C9MEN1KMT2AMAPT | |
| SCHEMBL18035897 | 0.77 | GRIA1 (0.44) | TSHRGRB2CYP2C9MEN1KMT2A | |
| SCHEMBL5283118 | 0.74 | GRIA1 (0.47) | TSHRCYP2C9MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776535-B2 | Site-specific incorporation of fluorinated amino acids into proteins | FRANKLIN AND MARSHALL COLLEGE (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776535-B2 | Site-specific incorporation of fluorinated amino acids into proteins | FRANKLIN AND MARSHALL COLLEGE (US) | 2010-08-17 | — | — | US | disclosed |