Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 8/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 8/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971633 | 1.00 | GRIA1 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL23682935 | 0.91 | GRIA1 (0.46) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL158168 | 0.88 | MAPT (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL4626004 | 0.88 | MAPT (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL43843 | 0.88 | MAPT (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5283079 | 0.82 | USP2 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5324038 | 0.82 | USP2 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5283118 | 0.81 | GRIA1 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL7281327 | 0.81 | GRIA1 (0.47) | GRIA1GRIA3GRIA4GRIA2GRIK5 | |
| SCHEMBL5282915 | 0.81 | USP2 (0.46) | GRIA1GRIA3GRIA4GRIA2GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479526-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | University of Iowa Research Foundation (US) | 2024-12-25 | — | — | EP | claimed |
| WO-2023158761-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | WO | claimed |
| EP-4479526-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | University of Iowa Research Foundation (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023158761-A1 | SITE-SPECIFIC ENCODING OF FLUORINATED PHENYLALANINE RESIDUES IN BACTERIAL AND MAMMALIAN CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | WO | disclosed |
| US-7776535-B2 | Site-specific incorporation of fluorinated amino acids into proteins | FRANKLIN AND MARSHALL COLLEGE (US) | 2010-08-17 | — | — | US | disclosed |
| US-20070218483-A1 | SITE-SPECIFIC INCORPORATION OF FLUORINATED AMINO ACIDS INTO PROTEINS | FRANKLIN AND MARSHALL COLLEGE (US) | 2007-09-20 | — | — | US | disclosed |