SCHEMBL43843

SCHEMBL43843

NC(Cc1c(F)c(F)c(F)c(F)c1F)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
CYP2C9 P11712 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
BLM P54132 3/20 0.47
USP2 O75604 2/20 0.47
PKM P14618 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 2/20 0.47
RGS12 O14924 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
NFKB1 P19838 1/20 0.47
CASP1 P29466 1/20 0.47
BRCA1 P38398 1/20 0.47
THPO P40225 1/20 0.47
CASP7 P55210 1/20 0.47
GNAI1 P63096 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4626004 1.00 MAPT (0.47) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL158168 1.00 MAPT (0.47) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL5324038 0.90 USP2 (0.47) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL5283079 0.90 USP2 (0.47) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL2971633 0.88 GRIA1 (0.47) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL2971635 0.88 GRIA1 (0.47) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL5282915 0.88 USP2 (0.46) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL23682935 0.86 GRIA1 (0.46) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL13205282 0.85 TSHR (0.42) MAPTCYP2C9MEN1KMT2ABLM
SCHEMBL5285947 0.84 USP2 (0.50) MAPTCYP2C9MEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2871 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731268-A1 CROSS-LINKED VESICLES WITH LOW-BOILING POINT FLUORINATED COMPOUND Bracco Suisse SA (CH) 2026-04-29 EP claimed
US-20260014283-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES FOR SPATIALLY RESOLVED MOLECULE DELIVERY AND METHODS OF USING THE SAME PENN STATE RES FOUND (US) 2026-01-15 US claimed
EP-4637837-A1 CATIONIC CROSS-LINKED VESICLES Bracco Suisse SA (CH) 2025-10-29 EP claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
EP-4554957-A1 ANTIVIRAL CYCLIC COMPOUNDS Universiteit Utrecht Holding B.V. (NL) 2025-05-21 EP claimed
WO-2025090926-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES WITH SURFACE-BOUND GENE EDITING TOOLS FOR SPATIALLY RESOLVED MOLECULE DELIVERY THE PENN STATE RESEARCH FOUNDATION (US) 2025-05-01 WO claimed
CN-119868594-A Method for radiolabelling GRPR antagonist and kit thereof 诺华股份有限公司 2025-04-25 CN claimed
US-20250111889-A1 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES UNIVERSITY OF WASHINGTON 2025-04-03 US claimed
CN-119715853-A Semi-quantitative assessment method for substitution degree of non-protein amino acid 遵义医科大学 2025-03-28 CN claimed
EP-4522221-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS Entrada Therapeutics, Inc. (US) 2025-03-19 EP claimed
US-20040072743-A1 Pharmaceutical composition of modified pna molecules PANTHECO A/S (DK) 2004-04-15 US claimed
EP-1296718-A1 PHARMACEUTICAL COMPOSITION OF MODIFIED PNA MOLECULES Pantheco A/S (DK) 2003-04-02 EP claimed
WO-2001076636-A2 PHARMACEUTICAL COMPOSITION OF MODIFIED PNA MOLECULES PANTHECO A/S (DK) 2001-10-18 WO claimed
US-6262229-B1 OCTAPEPTIDES BIOMEASURE INCORPORATED 2001-07-17 US claimed
US-6232305-B1 ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS NAEJA PHARMACEUTICAL INC. (CA) 2001-05-15 US claimed
EP-1025127-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES Wapharm AB (SE) 2000-08-09 EP claimed
EP-0950046-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (CA) 1999-10-20 EP claimed
WO-1998037097-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES WAPHARM AB (SE) 1998-08-27 WO claimed
WO-1998012176-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (US) 1998-03-26 WO claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed