SCHEMBL132090

SCHEMBL132090

CCOC(=O)C1CCCNC1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 2/20 0.53
SLC6A11 P48066 1/20 0.53
TSHR P16473 1/20 0.53
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
SLC6A13 Q9NSD5 1/20 0.53
MAPT P10636 4/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
CYP2D6 P10635 1/20 0.52
ALDH1A1 P00352 3/20 0.47
PKM P14618 1/20 0.43
MEN1 O00255 1/20 0.43
NOS2 P35228 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132089 1.00 SLC6A1 (0.53) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
SCHEMBL134525 1.00 SLC6A1 (0.53) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL5215224 0.98 SLC6A1 (0.52) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL22444028 0.98 SLC6A1 (0.52) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL205293 0.98 SLC6A1 (0.52) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
SCHEMBL14525966 0.95 ALDH1A1 (0.50) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
SCHEMBL29295425 0.93 ALDH1A1 (0.53) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
Chloroacetic Acid SCHEMBL27501180 0.91 SLC6A1 (0.49) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
Cadaverine Tartrate SCHEMBL4889376 0.89 SLC6A1 (0.47) SLC6A1SLC6A11TSHRLMNASMN1; SMN2
Cadaverine Tartrate SCHEMBL6970212 0.89 SLC6A1 (0.47) SLC6A1SLC6A11TSHRLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119968375-A Heterocyclic derivatives as Janus kinase inhibitors 奇斯药制品公司 2025-05-09 CN claimed
CN-119613607-A Preparation method of 193nm photoresist resin 江苏集萃光敏电子材料研究所有限公司 2025-03-14 CN claimed
CN-118986992-A Application of piperidine carboxylic acid ester compound in preparation of malignant tumor medicine 苏州大学 2024-11-22 CN claimed
CN-118910627-A Method for electrochemically synthesizing methylene quinone compound 西北师范大学 2024-11-08 CN claimed
CN-118184650-A 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof 中国人民解放军北部战区总医院 2024-06-14 CN claimed
CN-114656348-A Improved preparation method of methylene quinone compound 西北师范大学 2022-06-24 CN claimed
CN-110452130-B Obovatol Mannich base derivative and preparation method and application thereof 山西农业大学 2022-03-01 CN claimed
CN-110437191-B 13-amino xanthatin derivative and preparation method and application thereof 山西农业大学 2021-05-04 CN claimed
US-8530650-B2 2, 5-diamino-substituted pyrido [4, 3-D] pyrimidines as autotaxin inhibitors against cancer MERCK PATENT GMBH (DE) 2013-09-10 US claimed
CN-103159668-A 2-hydroxy-4-oxo-2-butenoic acid compound and pharmaceutical application thereof TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE 2013-06-19 CN claimed
CN-1401319-A Use of GABA transport protein inhibitor in preparing medicine for treating alcohol habituation and abuse SHANGHAI INST OF LIFE SCI CHIN (CN) 2003-03-12 CN claimed
CN-1382441-A Application of gammalon transporter inhibitor in preparing analgesic SHANGHAI INST OF LIFE SCIENCES (CN) 2002-12-04 CN claimed
EP-1218384-A4 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2002-11-20 EP claimed
EP-1218384-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2002-07-03 EP claimed
WO-2001023392-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-04-05 WO claimed
EP-0188805-B1 1,3-DITHIOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-09-06 EP claimed
EP-0327324-A2 Improved halogenated bis-imide flame retardants ALBEMARLE CORPORATION (US) 1989-08-09 EP claimed
US-4737494-A 2-YLIDENE AMMONIUM COMPOUNDS USED IN TREATING LIVER DISEASES BANYU PHARMACEUTICAL CO., LTD. (JP) 1988-04-12 US claimed
EP-0188805-A1 1,3-Dithiole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-07-30 EP claimed
US-4419354-A IMMUNOLOGY, ANTITUMOR AGENTS AMERICAN CYANAMID COMPANY (US) 1983-12-06 US claimed