SCHEMBL13209171

SCHEMBL13209171

Cc1cc(I)cc(C(=O)NC2(C3CC3)CC2)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MALT1 Q9UDY8 3/20 0.34
▸ TRPV1 Q8NER1 2/20 0.34
▸ CRACR2A Q9BSW2 5/20 0.34
▸ KLKB1 P03952 5/20 0.34
▸ OPRL1 P41146 1/20 0.34
▸ MAPK13 O15264 1/20 0.33
▸ MAPK12 P53778 1/20 0.33
▸ MAPK11 Q15759 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ DHODH Q02127 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13650107 0.90 KLKB1 (0.36) MALT1TRPV1KLKB1OPRL1
SCHEMBL958266 0.86 CARM1 (0.38) MALT1TRPV1KLKB1KDM4EMEN1
SCHEMBL6532873 0.85 PDE4B (0.36) KLKB1KDM4EMEN1ALDH1A1MAPT
SCHEMBL31059977 0.85 F10 (0.40) TRPV1KLKB1KDM4EMEN1ALDH1A1
SCHEMBL12911652 0.84 PDE4B (0.36) TRPV1KLKB1KDM4EMEN1ALDH1A1
SCHEMBL10028766 0.84 CARM1 (0.35) TRPV1KLKB1KDM4EMEN1ALDH1A1
SCHEMBL4491830 0.84 PDE4B (0.35) TRPV1KLKB1OPRL1KDM4EMEN1
SCHEMBL13104940 0.84 ORAI1 (0.34) MALT1TRPV1CRACR2AKLKB1KDM4E
SCHEMBL16622523 0.83 PDE4B (0.35) TRPV1KLKB1KDM4EMEN1ALDH1A1
SCHEMBL11960059 0.83 F10 (0.38) TRPV1KLKB1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871760-B1 CYANO ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-08-11 — — EP disclosed
US-7601743-B2 Cyano anthranilamide insecticides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-13 — — US disclosed
US-7601743-B2 Cyano anthranilamide insecticides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-13 — — US disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 — — US disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182750-A1 Cyano Anthranilamide Insecticides CRY1, CRYAA, ALDH7A1 MALT1 3077/4885TRPV1 2652/4885CRACR2A 3886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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