SCHEMBL13650107

SCHEMBL13650107

Cc1cc(C#N)cc(C(=O)NC2(C3CC3)CC2)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KLKB1 P03952 15/20 0.36
▸ OPRL1 P41146 1/20 0.34
▸ SLC2A1 P11166 1/20 0.34
▸ SLC2A2 P11168 1/20 0.34
▸ SLC2A3 P11169 1/20 0.34
▸ SLC2A4 P14672 1/20 0.34
▸ TRPV1 Q8NER1 1/20 0.33
▸ MALT1 Q9UDY8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13209171 0.90 MALT1 (0.34) KLKB1OPRL1TRPV1MALT1
SCHEMBL12113619 0.89 OPRL1 (0.34) KLKB1OPRL1SLC2A1SLC2A2SLC2A3
SCHEMBL782240 0.87 SLC2A1 (0.38) KLKB1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL10279937 0.86 KLKB1 (0.35) KLKB1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL4154454 0.86 KLKB1 (0.41) KLKB1
SCHEMBL11893156 0.85 SLC2A1 (0.37) KLKB1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL960289 0.85 SLC2A1 (0.42) KLKB1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL31059991 0.85 SLC2A1 (0.42) KLKB1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL12113624 0.85 CACNA1H (0.32) OPRL1SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL782144 0.85 KLKB1 (0.37) KLKB1OPRL1SLC2A1SLC2A2SLC2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601743-B2 Cyano anthranilamide insecticides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-13 — — US disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182750-A1 Cyano Anthranilamide Insecticides CRY1, CRYAA, ALDH7A1 KLKB1 4334/4885OPRL1 3722/4885SLC2A1 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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