Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210545 | 0.88 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210529 | 0.84 | RAB9A (0.71) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210704 | 0.84 | KMT2A (0.81) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6450945 | 0.82 | KMT2A (0.84) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210546 | 0.82 | ALDH1A1 (0.70) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13210581 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30834320 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5974770 | 0.81 | KMT2A (0.73) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5211749 | 0.80 | RAB9A (0.74) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15907194 | 0.80 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | CBR3, CYCS, CYC1 | ALDH1A1 3151/4885POLB 3734/4885KMT2A 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.