Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210583 | 0.88 | ALDH1A1 (0.79) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13210546 | 0.82 | ALDH1A1 (0.70) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13210581 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30834320 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13986890 | 0.80 | RAB9A (0.77) | ALDH1A1POLBMEN1KMT2ARAB9A | |
| SCHEMBL13210715 | 0.79 | P4HTM (0.78) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13210711 | 0.79 | P4HTM (0.78) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13210717 | 0.79 | ALDH1A1 (0.65) | ALDH1A1POLBRAB9ANPC1KDM4E | |
| SCHEMBL13210529 | 0.78 | RAB9A (0.71) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7745878 | 0.78 | KCNK3 (0.82) | POLBMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | CBR3, CYCS, CYC1 | ALDH1A1 3151/4885POLB 3734/4885SMN1; SMN2 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.