Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117632 | 0.86 | PDCD1 (0.45) | TDP1THRBPDCD1CD274ALDH1A1 | |
| SCHEMBL13117620 | 0.77 | ALDH1A1 (0.47) | TDP1THRBPDCD1CD274ALDH1A1 | |
| SCHEMBL13117746 | 0.76 | FFAR1 (0.43) | PDCD1CD274ALDH1A1PPARGPPARD | |
| SCHEMBL13117445 | 0.76 | KDM4E (0.46) | TDP1THRBPDCD1CD274ALDH1A1 | |
| SCHEMBL13213353 | 0.73 | VDR (0.34) | PDCD1CD274 | |
| SCHEMBL10030191 | 0.71 | TDP1 (0.55) | TDP1THRBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2907137 | 0.71 | CD274 (0.38) | PDCD1CD274C5AR1 | |
| SCHEMBL17459123 | 0.70 | L3MBTL1 (0.64) | TDP1THRBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13117624 | 0.70 | CD274 (0.40) | PDCD1CD274FFAR1RAD52 | |
| SCHEMBL5694355 | 0.69 | TDP1 (0.56) | TDP1THRBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216330-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-08-11 | — | — | EP | disclosed |