SCHEMBL132151

SCHEMBL132151

Clc1ccc(Br)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29844469 1.00
Formaldehyde SCHEMBL28006714 0.93 L3MBTL1 (0.41)
SCHEMBL17157352 0.82 LTA4H (0.48)
SCHEMBL17157314 0.79 LIPE (0.43)
Ethoxycarbonyl Group SCHEMBL28039599 0.76 NPSR1 (0.39)
SCHEMBL29740319 0.73 CYP19A1 (0.44)
SCHEMBL787481 0.73 CYP19A1 (0.44)
SCHEMBL14465780 0.72
SCHEMBL17800 0.71
SCHEMBL16841 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390645-A Dehalogenation method for reducing N heteroaryl halide by using hydrosilane 浙江科技大学 2025-02-07 CN claimed
CN-117777010-A 2-acetyl-5-chloropyridine and preparation method thereof 常熟泓德生物科技有限公司 2024-03-29 CN claimed
CN-112047925-A Preparation method of N- (aryl/heteroaryl) alkyl-diamide 中国科学院兰州化学物理研究所 2020-12-08 CN claimed
CN-106674095-A 2-amino-3-bromine-5-chlorin-1-(2-(4-bromophenyl)-2-oxoethyl) pyridinium bromide 山东友帮生化科技有限公司 2017-05-17 CN claimed
CN-106467488-A A kind of preparation technology of 2 iodine, 3 bromine 5 chloropyridine 贵州大学 2017-03-01 CN claimed
CN-104016909-B The synthetic method of the bromo-5-chloropyridine of a kind of 2-amino-3- Dingyao County You Bang Chemical Co., Ltd. (CN) 2016-04-20 CN claimed
CN-104016909-A Synthetic method of 2-amino-3-bromo-5-chloropyridine DINGTAO COUNTY YOUBANG CHEMICAL INDUSTRY CO LTD 2014-09-03 CN claimed
US-12606566-B2 Substituted cyclopenta[4,5]pyrrolo[1,2-a]pyrazines as bruton's tyrosine kinase inhibitors SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) 2026-04-21 US disclosed
US-12583851-B2 Heteroaryl-substituted pyrazine derivatives as pesticides ELANCO ANIMAL HEALTH GMBH (DE) 2026-03-24 US disclosed
EP-4705296-A1 HETEROARYLINDOLE INHIBITORS OF APOL-1 OmniAB, Inc. (US) 2026-03-11 EP disclosed
US-20260028326-A1 COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF GLUETACS THERAPEUTICS SHANGHAI CO LTD (CN) 2026-01-29 US disclosed
US-20260026253-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-01-22 US disclosed
EP-4676480-A1 INHIBITORS OF DNA POLYMERASE THETA Breakpoint Therapeutics GmbH (DE) 2026-01-14 EP disclosed
EP-0097480-A1 Triazole antifungal agents Pfizer Limited (GB) 1984-01-04 EP disclosed
EP-0097014-A2 Triazole antifungal agents Pfizer Limited (GB) 1983-12-28 EP disclosed
EP-0096569-A2 Triazole antifungal agents Pfizer Limited (GB) 1983-12-21 EP disclosed
EP-0011142-B1 PYRIDO (2,1-B) QUINAZOLINONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1982-12-29 EP disclosed
EP-0013145-A2 Substituted anilinopyridines, processes for their preparation and intermediates for use therein, compositions and herbicidal use thereof ICI AUSTRALIA LIMITED (AU) 1980-07-09 EP disclosed
EP-0011142-A1 Pyrido (2,1-b) quinazolinones, their preparation and pharmaceutical compositions containing them SCHERING AKTIENGESELLSCHAFT (DE) 1980-05-28 EP disclosed
US-3947457-A Method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines THE DOW CHEMICAL COMPANY (US) 1976-03-30 US disclosed