SCHEMBL1322296

SCHEMBL1322296

COc1ccc2c(c1)C(C)=CC(C)(C)N2

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.74
MAPT P10636 9/20 0.74
KDM4E B2RXH2 8/20 0.74
MEN1 O00255 5/20 0.74
KMT2A Q03164 5/20 0.74
HPGD P15428 7/20 0.70
HSD17B10 Q99714 6/20 0.70
LMNA P02545 6/20 0.70
TDP1 Q9NUW8 4/20 0.70
CYP3A4 P08684 2/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2D6 P10635 1/20 0.70
CYP2C9 P11712 1/20 0.70
ALOX15 P16050 1/20 0.70
ALOX12 P18054 1/20 0.70
CYP2C19 P33261 1/20 0.70
HIF1A Q16665 1/20 0.70
L3MBTL1 Q9Y468 4/20 0.59
MAPK1 P28482 1/20 0.59
HTT P42858 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29430126 0.87 ALDH1A1 (0.97) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL1394706 0.87 ALDH1A1 (0.97) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL11453544 0.85 ALDH1A1 (0.61) ALDH1A1MAPTKDM4EMEN1KMT2A
Bromide SCHEMBL7802438 0.85 ALDH1A1 (0.94) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL4172332 0.84 PGR (0.70) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL11154652 0.84 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL11157939 0.84 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL12670563 0.83 MAPT (0.67) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL11598567 0.83 LMNA (0.65) ALDH1A1MAPTKDM4EMEN1KMT2A
E324 SCHEMBL7999894 0.83 ALDH1A1 (1.00) ALDH1A1MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4424802-B1 LUBRICANT COMPOSITION NOF CORP (JP) 2026-05-27 EP claimed
CN-105602677-B Hydraulic oil composition 日油株式会社 2020-01-17 CN claimed
US-4196113-A ADDUCT OF A BUTADIENE POLYMER AND AN A,B-ACID, A 1,2-DIHYDROQUINOLINE GELATING INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1980-04-01 US claimed
US-4176109-A CORROSION RESISTANCE, IMPACT RESISTANCE, ADHESIONN; ADDUCT OF BUTAC SOLVENT, NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1979-11-27 US claimed
US-3952023-A Method for preparing adduct of butadiene polymer or copolymer and α, β-ethylenically unsaturated dicarboxylic acid compound NIPPON OIL COMPANY LTD. (JA) 1976-04-20 US claimed
EP-4424802-B1 LUBRICANT COMPOSITION NOF CORP (JP) 2026-05-27 EP disclosed
US-20250346826-A1 LUBRICANT COMPOSITION NOF CORPORATION (JP) 2025-11-13 US disclosed
US-12398339-B2 Lubricating oil composition NOF CORPORATION (JP) 2025-08-26 US disclosed
US-20250230377-A1 LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 2025-07-17 US disclosed
EP-4509585-A1 LUBRICATING OIL COMPOSITION NOF Corporation (JP) 2025-02-19 EP disclosed
EP-4424802-A1 LUBRICANT COMPOSITION NOF Corporation (JP) 2024-09-04 EP disclosed
EP-3470498-B1 LUBRICANT BASE OIL NOF CORP (JP) 2023-11-15 EP disclosed
US-4196112-A ADDUCT OF A BUTADIENE POLYMER AN A,B-ACID, A CARBOCYCLIC ALCOHOL GELATION INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1980-04-01 US disclosed
US-4196113-A ADDUCT OF A BUTADIENE POLYMER AND AN A,B-ACID, A 1,2-DIHYDROQUINOLINE GELATING INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1980-04-01 US disclosed
US-4176109-A CORROSION RESISTANCE, IMPACT RESISTANCE, ADHESIONN; ADDUCT OF BUTAC SOLVENT, NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1979-11-27 US disclosed
US-4175068-A ADDUCT OF BUTADIENE AND UNSATURATED DICARBOXYLIC ACID, NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1979-11-20 US disclosed
US-4171308-A ADDUCT OF A BUTADIENE POLYMER AND AN A,B-UNSATURATED CARBOXY ACID COMPOUND, NEUTRALIZED NIPPON OIL CO. LTD. (JP) 1979-10-16 US disclosed
US-4145501-A ADDUCT OF A LOW MOLECULAR WEIGHT BUTADIENE POLYMER AND AN UNSATURATED DICARBOXYLIC ACID COMPOUND, CORROSION RESISTANT, ADHESION, IMPACT RESISTANT NIPPON OIL CO., LTD. (JP) 1979-03-20 US disclosed
US-4079153-A SUPPRESSING FORMATION OF NITROSAMINES BY INTRODUCING A 1,2-DIHYDROQUINOLINE INTO MEAT LEVER BROTHERS COMPANY (US) 1978-03-14 US disclosed
US-3952023-A Method for preparing adduct of butadiene polymer or copolymer and α, β-ethylenically unsaturated dicarboxylic acid compound NIPPON OIL COMPANY LTD. (JA) 1976-04-20 US disclosed