Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002299 | 0.86 | MAPK1 (0.34) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19NPC1 | |
| SCHEMBL13245893 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL12733209 | 0.83 | HSPA5 (0.41) | SMN1; SMN2HSPA5CYP2C9CYP2C19HIF1A | |
| SCHEMBL14566262 | 0.82 | CA2 (0.35) | ALDH1A1CA2 | |
| SCHEMBL13652813 | 0.80 | ESR1 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL12774894 | 0.79 | TSHR (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL17717937 | 0.78 | NPC1 (0.58) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL12733203 | 0.77 | HSPA5 (0.63) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL14607286 | 0.76 | GABRA1 (0.37) | ALDH1A1POLBCYP2C19NPC1RAB9A | |
| SCHEMBL13652815 | 0.76 | CYP3A4 (0.34) | SMN1; SMN2ALDH1A1CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298455-B2 | Alignment material composition and alignment layer | AU OPTRONICS CORPORATION (TW) | 2012-10-30 | — | — | US | disclosed |
| US-20100213423-A1 | ALIGNMENT MATERIAL COMPOSITION AND ALIGNMENT LAYER | AU OPTRONICS CORPORATION (TW) | 2010-08-26 | — | — | US | disclosed |