SCHEMBL9002299

SCHEMBL9002299

CCC(C)(C)c1cc(-n2n3c4ccccc4n23)c(O)c(C(C)(C)CC)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.34
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CASP3 P42574 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ SENP8 Q96LD8 1/20 0.34
▸ SENP7 Q9BQF6 1/20 0.34
▸ SENP6 Q9GZR1 1/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ MITF O75030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12774894 0.93 TSHR (0.41) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL13652815 0.89 CYP3A4 (0.34) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL12733198 0.87 CYP2C19 (0.35) MAPK1SMN1; SMN2ATMNPSR1CYP1A2
SCHEMBL13223648 0.86 SMN1; SMN2 (0.36) SMN1; SMN2NPC1RAB9ACYP2C9CYP2C19
SCHEMBL12733209 0.83 HSPA5 (0.41) SMN1; SMN2CYP2C9CYP2C19
SCHEMBL14566262 0.82 CA2 (0.35) ATMTSHRALDH1A1KDM4E
SCHEMBL13652839 0.80 CYP3A4 (0.34) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL13652835 0.80 ACSS2 (0.35) SMN1; SMN2ALDH1A1KDM4E
SCHEMBL9002281 0.79 TSHR (0.46) MAPK1SMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL5080637 0.78 KCNMA1 (0.47) MAPK1SMN1; SMN2LMNARAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9778511-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2017-10-03 — — US disclosed
US-9778511-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2017-10-03 — — US disclosed
US-9740060-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2017-08-22 — — US disclosed
US-9740060-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2017-08-22 — — US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-9417480-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 — — US disclosed
US-9417480-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 — — US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 — — US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 — — US disclosed
US-7318951-B2 Retardation film, producing process thereof and liquid crystal display utilizing the same FUJIFILM CORPORATION (JP) 2008-01-15 — — US disclosed
US-20070292635-A1 Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070285603-A1 Transparent Film And Optical Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device Employing It FUJI PHOTO FILM CO., LTD. (JP) 2007-12-13 — — US disclosed
US-20070273815-A1 Cellulose acylate film, production method of cellulose acylate film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2007-11-29 — — US disclosed
US-20070135538-A1 Non-halogen flame-retardant resin composition SHIN-ETSU CHEMICAL CO., LTD. 2007-06-14 — — US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 — — US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 — — US disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 — — US disclosed
US-20070032381-A1 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2007-02-08 — — US disclosed
US-20070032381-A1 Heat-sensitive recording material, heat-sensitive recording method and method for manufacturing heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2007-02-08 — — US disclosed
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