Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906448 | 0.84 | RAB9A (0.49) | ALDH1A1RAB9AKMT2AMEN1ALOX5 | |
| SCHEMBL21246195 | 0.82 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1KMT2AALOX5UTS2R | |
| SCHEMBL2255946 | 0.81 | KMT2A (0.49) | ALDH1A1L3MBTL1KMT2AMEN1ALOX5 | |
| SCHEMBL21227048 | 0.81 | ALOX5 (0.43) | FAAHL3MBTL1RAB9AKMT2AMEN1 | |
| SCHEMBL4662624 | 0.81 | TAAR1 (0.46) | KMT2AALOX5HPGD | |
| SCHEMBL3988521 | 0.81 | ALOX5 (0.62) | ALDH1A1FKBP1ARAB9AALOX5NPC1 | |
| SCHEMBL3874037 | 0.81 | ALOX5 (0.51) | FAAHALDH1A1KMT2AALOX5HPGD | |
| SCHEMBL1727025 | 0.80 | KMT2A (0.62) | ALDH1A1L3MBTL1RAB9AKMT2AMEN1 | |
| SCHEMBL3868264 | 0.80 | ALOX5 (0.50) | FAAHALDH1A1KMT2AALOX5UTS2R | |
| SCHEMBL4602017 | 0.78 | KDM4E (0.45) | ALDH1A1RAB9AKMT2AMEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130030017-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ANDRIES KOENRAAD JOZEF LODEWIJK MARCEL (BE) | 2013-01-31 | — | — | US | disclosed |
| US-20100204270-A1 | Quinoline Derivatives as Antibacterial Agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-08-12 | — | — | US | disclosed |
| US-20100204270-A1 | Quinoline Derivatives as Antibacterial Agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-08-12 | — | — | US | disclosed |
| WO-2007000436-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204270-A1 | Quinoline Derivatives as Antibacterial Agents | NQO2, NDUFB7, NQO1 | FAAH 2928/4885ALDH1A1 1171/4885L3MBTL1 3449/4885 |
| US-20130030017-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | NQO2, NDUFB7, NDUFA7 | FAAH 4010/4885ALDH1A1 1777/4885L3MBTL1 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.