SCHEMBL132274

SCHEMBL132274

COC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 8/20 1.00
L3MBTL1 Q9Y468 2/20 0.71
MEN1 O00255 1/20 0.71
ABL1 P00519 1/20 0.71
LMNA P02545 1/20 0.71
PKM P14618 1/20 0.71
IDE P14735 1/20 0.71
MAPK1 P28482 1/20 0.71
KMT2A Q03164 1/20 0.71
RIN1 Q13671 1/20 0.71
HLCS P50747 6/20 0.64
CA12 O43570 3/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA9 Q16790 3/20 0.54
HPSE Q9Y251 1/20 0.54
PPARG P37231 2/20 0.52
NR2E3 Q9Y5X4 2/20 0.52
NCOR2 Q9Y618 2/20 0.52
MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19170150 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL10047674 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL10047701 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL565879 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL10171691 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL19267509 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL20216901 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL21488759 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL20844951 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA
SCHEMBL14617995 1.00 TDP1 (1.00) TDP1L3MBTL1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
WO-2026107515-A1 INCRETIN HORMONE COMPOSITIONS AND METHODS USING SAME DIASOME PHARMACEUTICALS, INC. (US) 2026-05-21 WO claimed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
CN-119395003-A Kit, microfluidic device and method for performing biotin assays 美国西门子医学诊断股份有限公司 2025-02-07 CN claimed
US-20250027947-A1 KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2025-01-23 US claimed
CN-112424589-B Kit, microfluidic device and method for performing biotin assays 美国西门子医学诊断股份有限公司 2025-01-14 CN claimed
EP-3830556-B1 KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2024-11-13 EP claimed
US-12140596-B2 Kits, microfluidics devices, and methods for performing biotin assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-11-12 US claimed
WO-2024182425-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASES/DISORDERS NOUREDDINE ACHRAF (US) 2024-09-06 WO claimed
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. 2010-05-27 US claimed
WO-2009042945-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (AN OHIO CORPORATION ) (US) 2009-04-02 WO claimed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US claimed
CN-101237854-A Lipid construct for delivery of insulin to a mammal SDG INC (US) 2008-08-06 CN claimed
CN-101237855-A Lipid construct for delivery of interferon to a mammal SDG INC (US) 2008-08-06 CN claimed
EP-1883394-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
EP-1883395-A2 LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
WO-2006127361-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
WO-2006127360-A2 LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
EP-0088542-B1 SKIN TREATMENT COMPOSITION UNILEVER N.V. (NL) 1988-05-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL HAVCR2, IFNAR1, IFNG TDP1 4713/4885L3MBTL1 3129/4885MEN1 4095/4885
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 TDP1 4819/4885L3MBTL1 3625/4885MEN1 966/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 TDP1 4755/4885L3MBTL1 3724/4885MEN1 2415/4885
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL GPR119, INSR, FABP1 TDP1 4833/4885L3MBTL1 2520/4885MEN1 2073/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 TDP1 4757/4885L3MBTL1 2707/4885MEN1 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.