Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MDM4 | O15151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27081455 | 0.86 | CASP3 (0.53) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL7604717 | 0.86 | CASP3 (0.54) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL119338 | 0.86 | CASP3 (0.60) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL119534 | 0.86 | CASP3 (0.60) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL27081834 | 0.84 | CASP3 (0.52) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL119273 | 0.83 | CASP3 (0.54) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL119042 | 0.83 | CASP3 (0.54) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL30191464 | 0.82 | MDM4 (0.60) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL13209783 | 0.82 | MDM4 (0.60) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL8653790 | 0.81 | MDM4 (0.59) | CASP3KMT2AMDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785825-B2 | Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-08-31 | — | — | US | disclosed |