Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.77 |
| ▸ | MMP9 | P14780 | 6/20 | 0.77 |
| ▸ | MMP3 | P08254 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenobarbital SCHEMBL2592325 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL18825042 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL16583 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL28099657 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL6807467 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL3475428 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL352763 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL4193755 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL22032658 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL2120028 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132506-B1 | CARBOXYLATE LIGAND MODIFIED FERRIC IRON HYDROXIDE COMPOSITIONS FOR USE IN THE TREATMENT OR PREVENTION OF IRON DEFICIENCY ASSOCIATED WITH LIVER DISEASES | NEMYSIS LTD (IE) | 2024-05-15 | — | — | EP | disclosed |
| US-20240066053-A1 | Materials and Methods Relating to Stabilised Polymeric Silicate Compositions | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2024-02-29 | — | — | US | disclosed |
| US-11833171-B2 | Materials and methods relating to stabilised polymeric silicate compositions | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-12-05 | — | — | US | disclosed |
| US-11684572-B2 | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids and related compositions and uses | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-06-27 | — | — | US | disclosed |
| WO-2023078435-A1 | APPLICATION OF FOLIC ACID IN PREVENTION, DIAGNOSIS, AND TREATMENT OF HEREDITARY, INFECTIOUS, OR ALLERGIC DISEASES | 广州市妇女儿童医疗中心 | 2023-05-11 | — | — | WO | disclosed |
| CN-116077502-A | Use of folic acid in the prevention, diagnosis and treatment of genetic, infectious or allergic diseases | 广州市妇女儿童医疗中心 | 2023-05-09 | — | — | CN | disclosed |
| US-20230134391-A1 | Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases | NEMYSIS Ltd. (IE) | 2023-05-04 | — | — | US | disclosed |
| EP-4132506-A1 | CARBOXYLATE LIGAND MODIFIED FERRIC IRON HYDROXIDE COMPOSITIONS FOR USE IN THE TREATMENT OR PREVENTION OF IRON DEFICIENCY ASSOCIATED WITH LIVER DISEASES | Nemysis Limited (IE) | 2023-02-15 | — | — | EP | disclosed |
| WO-2022169634-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | UNM RAINFOREST INNOVATIONS (US) | 2022-08-11 | — | — | WO | disclosed |
| US-11406664-B2 | Ferric maltol compositions for use in the treatment or prevention of cancer and tumours | Shield TX (UK) Limited (GB) | 2022-08-09 | — | — | US | disclosed |
| WO-2012146890-A1 | PREBIOTIC AGENT | THE UNIVERSITY OF BIRMINGHAM (GB) | 2012-11-01 | — | — | WO | disclosed |
| US-20120276163-A1 | ANTI-CANCER COMPOSITION COMPRISING ALGINATE | THE UNIVERSITY OF BIRMINGHAM (GB) | 2012-11-01 | — | — | US | disclosed |
| EP-2493481-A1 | ANTI-CANCER COMPOSITION COMPRISING ALGINATE | The University of Birmingham (GB) | 2012-09-05 | — | — | EP | disclosed |
| WO-2012097155-A1 | IMPROVED PHARMACEUTICAL COMPOSITIONS FOR DELIVERY OF FERRIC IRON COMPOUNDS, AND METHODS OF USE THEREOF | CHIASMA INC. (US) | 2012-07-19 | — | — | WO | disclosed |
| US-8058462-B2 | Adding ligand then alkalinity agent to metal salt solution; precipitating such as iron hydroxide maleate; micronutrients | MEDICAL RESEARCH COUNCIL (GB) | 2011-11-15 | — | — | US | disclosed |
| WO-2011051665-A1 | ANTI-CANCER COMPOSITION COMPRISING ALGINATE | THE UNIVERSITY OF BIRMINGHAM (GB) | 2011-05-05 | — | — | WO | disclosed |
| EP-2125847-A1 | LIGAND MODIFIED POLY OXO-HYDROXY METAL ION MATERIALS, THEIR USES AND PROCESSES FOR THEIR PREPARATION | Medical Research Council (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008096130-A1 | LIGAND MODIFIED POLY OXO-HYDROXY METAL ION MATERIALS, THEIR USES AND PROCESSES FOR THEIR PREPARATION | MEDICAL RESEARCH COUNCIL (GB) | 2008-08-14 | — | — | WO | disclosed |
| US-20080188555-A1 | LIGAND MODIFIED POLY OXO-HYDROXY METAL ION MATERIALS, THEIR USES AND PROCESSES FOR THEIR PREPARATION | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2008-08-07 | — | — | US | disclosed |
| US-20060046982-A1 | Orthomolecular medical use of L-citrulline for capillary endothelial protection and adjacent cell protection in neurodegenerative disease | WAUGH WILLIAM H | 2006-03-02 | — | — | US | disclosed |