Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.77 |
| ▸ | MMP9 | P14780 | 6/20 | 0.77 |
| ▸ | MMP3 | P08254 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenobarbital SCHEMBL18825042 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL2592325 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL16583 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL28099657 | 0.98 | MMP2 (0.80) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL3475428 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL22032658 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL4193755 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL1322895 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL352763 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL2120028 | 0.96 | MMP2 (0.77) | MMP2MMP9MMP3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195857-A1 | USE OF A TRP MODULATOR FOR THE PROPHYLAXIS AND/OR ALLEVIATING OF GRASS TETANY AND/OR PARTURIENT PARESIS IN TYLOPODA OR RUMINANTS | Freie Universität Berlin (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-9693971-B2 | Compositions for alleviating gastrointestinal tract disorders or associated systemic disorders in ruminants and camelids | FREIE UNIVERSITÄT BERLIN (DE) | 2017-07-04 | — | — | US | disclosed |
| EP-2879662-B1 | COMPOSITION FOR ALLEVIATING GASTROINTESTINAL DEFECTS OR SYSTEMIC SYMPTOMES ASSOCIATED HEREWITH IN RUMINANTS AND CAMELIDS | FREIE UNIVERSITÄT BERLIN (DE) | 2017-02-08 | — | — | EP | disclosed |
| US-20150164822-A1 | COMPOSITIONS FOR ALLEVIATING GASTROINTESTINAL TRACT DISORDERS OR ASSOCIATED SYSTEMIC DISORDERS IN RUMINANTS AND CAMELIDS | PERFORMANAT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| CN-104705659-A | Instant protein powder rich in omega 3 acid and branched-chain amino acid and preparation method thereof | QIU XIA | 2015-06-17 | — | — | CN | disclosed |
| EP-2879662-A1 | COMPOSITIONS FOR ALLEVIATING GASTROINTESTINAL TRACT DISORDERS OR ASSOCIATED SYSTEMIC DISORDERS IN RUMINANTS AND CAMELIDS | Freie Universität Berlin (DE) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014020067-A1 | COMPOSITIONS FOR ALLEVIATING GASTROINTESTINAL TRACT DISORDERS OR ASSOCIATED SYSTEMIC DISORDERS IN RUMINANTS AND CAMELIDS | FREIE UNIVERSITÄT BERLIN (DE) | 2014-02-06 | — | — | WO | disclosed |
| US-20040224880-A1 | Regulation of gastric acid secretion by inwardly rectifying k+ channels | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2004-11-11 | — | — | US | disclosed |
| WO-2003011338-A1 | REGULATION OF GASTRIC ACID SECRETION BY INWARDLY RECTIFYING K+ CHANNELS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2003-02-13 | — | — | WO | disclosed |