Sugi Predict

Sugi Predict / Compounds / Phenobarbital

Phenobarbital

Phenobarbital

SCHEMBL3475428

CCC1(c2ccccc2)C(=O)NC(=O)NC1=O.[KH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 6/20 0.77
▸ MMP9 P14780 6/20 0.77
▸ MMP3 P08254 3/20 0.77
▸ KMT2A Q03164 2/20 0.66
▸ MEN1 O00255 1/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ POLB P06746 1/20 0.66
▸ TSHR P16473 1/20 0.66
▸ APEX1 P27695 1/20 0.66
▸ TDP1 Q9NUW8 1/20 0.66
▸ LMNA P02545 3/20 0.60
▸ CYP2C19 P33261 1/20 0.54
▸ MMP13 P45452 2/20 0.51
▸ MMP8 P22894 1/20 0.49
▸ CACNA1F O60840 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ HTR2A P28223 1/20 0.46
▸ HRH1 P35367 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenobarbital SCHEMBL18825042 0.98 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL2592325 0.98 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL16583 0.98 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL28099657 0.98 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL6807467 0.96 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL22032658 0.96 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL4193755 0.96 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL1322895 0.96 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL352763 0.96 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL2120028 0.96 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010017466-A2 PHENOBARBITAL SALTS; METHODS OF MAKING; AND METHODS OF USE THEREOF MUTUAL PHARMACEUTICAL COMPANY, INC. (US) 2010-02-11 — — WO claimed
US-20100035904-A1 PHENOBARBITAL SALTS; METHODS OF MAKING; AND METHODS OF USE THEREOF MUTUAL PHARMACEUTICAL COMPANY, INC., A PENNSYLVANIA CORPORATION 2010-02-11 — — US claimed
US-20240082161-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-03-14 — — US disclosed
US-11857683-B2 Stabilization of phenobarbital sodium for injection SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-01-02 — — US disclosed
WO-2023175542-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2023-09-21 — — WO disclosed
US-20230031957-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2023-02-02 — — US disclosed
WO-2023281441-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2023-01-12 — — WO disclosed
CN-112741811-A Novel continuous controllable drug delivery system for central nervous system drugs 江苏集萃新型药物制剂技术研究所有限公司 2021-05-04 — — CN disclosed
US-20190262453-A1 DESIGN AND COMPOSITION OF CELL-STABILIZED PHARMACEUTICAL FORMULATIONS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2019-08-29 — — US disclosed
WO-2010017466-A2 PHENOBARBITAL SALTS; METHODS OF MAKING; AND METHODS OF USE THEREOF MUTUAL PHARMACEUTICAL COMPANY, INC. (US) 2010-02-11 — — WO disclosed
US-20100035904-A1 PHENOBARBITAL SALTS; METHODS OF MAKING; AND METHODS OF USE THEREOF MUTUAL PHARMACEUTICAL COMPANY, INC., A PENNSYLVANIA CORPORATION 2010-02-11 — — US disclosed
US-20040191314-A1 Antiepileptic dosage form and process for protecting antiepileptic drug JAO FRANK 2004-09-30 — — US disclosed
US-20030056896-A1 Effective therapy for epilepsies JAO FRANK (US) 2003-03-27 — — US disclosed
US-5955103-A Dosage form comprising antiepileptic drug ALZA CORPORATION (US) 1999-09-21 — — US disclosed
US-5906832-A Method for treating epilepsies ALZA CORPORATION (US) 1999-05-25 — — US disclosed
US-5876750-A Effective therapy for epilepsies ALZA CORPORATION (US) 1999-03-02 — — US disclosed
US-5863558-A Effective therapy for epilepsies ALZA CORPORATION (US) 1999-01-26 — — US disclosed
US-5660861-A Effective therapy for epilepsies ALZA CORPORATION (US) 1997-08-26 — — US disclosed
EP-0758228-A1 EFFECTIVE DOSAGE FORM FOR ANTIEPILEPTIC DRUGS ALZA CORPORATION (US) 1997-02-19 — — EP disclosed
WO-1995029665-A1 EFFECTIVE DOSAGE FORM FOR ANTIEPILEPTIC DRUGS ALZA CORPORATION (US) 1995-11-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240082161-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION PYGB, EPM2A, CACNA1A MMP2 1007/4885MMP9 2479/4885MMP3 2771/4885
US-20230031957-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION EPM2A, PYGB, ATP6V1B2 MMP2 1175/4885MMP9 2497/4885MMP3 2462/4885
US-11857683-B2 Stabilization of phenobarbital sodium for injection EPM2A, PYGB, ATP6V1B2 MMP2 1175/4885MMP9 2497/4885MMP3 2462/4885
US-20190262453-A1 DESIGN AND COMPOSITION OF CELL-STABILIZED PHARMACEUTICAL FORMULATIONS CALU, ABCG2, ACTB MMP2 2730/4885MMP9 3350/4885MMP3 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.