Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | TST | Q16762 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13261881 | 0.88 | L3MBTL1 (0.47) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13013509 | 0.85 | ALDH1A1 (0.49) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2791873 | 0.84 | SMN1; SMN2 (0.53) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2791869 | 0.84 | SMN1; SMN2 (0.53) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13013513 | 0.83 | ALDH1A1 (0.40) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13062418 | 0.79 | ALDH1A1 (0.43) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3783878 | 0.77 | ALDH1A1 (0.53) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3769984 | 0.76 | ALDH1A1 (0.52) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3778699 | 0.76 | ALDH1A1 (0.52) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3771807 | 0.76 | ALDH1A1 (0.52) | KMT2AL3MBTL1MEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023889-B2 | Use of ascorbic acid derivatives for the functionalization of matrices | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-20100167936-A1 | USE OF ASCORBIC ACID DERIVATIVES FOR THE FUNCTIONALIZATION OF MATRICES | MERCK PATENT GESELLSCHAFT (DE) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167936-A1 | USE OF ASCORBIC ACID DERIVATIVES FOR THE FUNCTIONALIZATION OF MATRICES | PROC, TTPA, COX6C | KMT2A 4296/4885L3MBTL1 4596/4885MEN1 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.