Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849522 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL493442 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL13578674 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL14823101 | 0.78 | ALDH1A1 (0.78) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL6480086 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL4702952 | 0.78 | FDPS (0.51) | ALDH1A1TSHRAOX1FDPSTDP1 | |
| SCHEMBL12476044 | 0.77 | ALDH1A3 (0.53) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL17693601 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRAOX1FDPSALDH1A3 | |
| SCHEMBL3721435 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRAOX1FDPSTDP1 | |
| SCHEMBL15580939 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRAOX1FDPSALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168151-A1 | NOVEL PROCESSES FOR PREPARING 6-(DIFLUOROMETHOXY)[1]BENZOFURO[3,2-C]PYRIDINE-9-CARBALDEHYDE, A NOVEL INTERMEDIATE FOR THE SYNTHESIS OF PDE IV INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168151-A1 | NOVEL PROCESSES FOR PREPARING 6-(DIFLUOROMETHOXY)[1]BENZOFURO[3,2-C]PYRIDINE-9-CARBALDEHYDE, A NOVEL INTERMEDIATE FOR THE SYNTHESIS OF PDE IV INHIBITORS | PDE4B, PDE4A, PDE4C | ALDH1A1 341/4885TSHR 3854/4885AOX1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.