SCHEMBL132336

SCHEMBL132336

CC(=O)Oc1ccc(Cl)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56
HTR2B P41595 1/20 0.56
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
HIF1A Q16665 1/20 0.53
MAPT P10636 3/20 0.50
KDM4E B2RXH2 3/20 0.49
TP53 P04637 1/20 0.49
ALOX15 P16050 1/20 0.49
ALDH1A1 P00352 2/20 0.48
ABCB11 O95342 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
LMNA P02545 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
HTT P42858 3/20 0.47
GAA P10253 2/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712913 0.98 TSHR (0.54) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL13342741 0.85 KDM4E (0.60) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL11716516 0.85 TSHR (0.56) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL6273604 0.85 TSHR (0.60) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL6869400 0.85 ACHE (0.59) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL11338058 0.84 KDM4E (0.58) TSHRMAPTKDM4ETP53ALDH1A1
Hydrochloric Acid SCHEMBL11854026 0.83 TSHR (0.58) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL134715 0.82 KMT2A (0.57) TSHRMAPTKDM4EALDH1A1ABCB11
SCHEMBL13342760 0.82 MAPT (0.59) TSHRHTR2AHTR2CHTR2BCYP1A2
SCHEMBL13342826 0.81 TSHR (0.57) TSHRHTR2AHTR2CHTR2BCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402622-B2 Agricultural compositions and methods of use thereof VALENT U.S.A., LLC (US) 2025-09-02 US claimed
US-12239130-B2 Encapsulation of herbicides to reduce crop injury MONSANTO TECHNOLOGY LLC (US) 2025-03-04 US claimed
US-12084435-B2 Pyridine ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2024-09-10 US claimed
US-12024500-B2 Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2024-07-02 US claimed
EP-4218413-A2 NON-AQUEOUS SOLUTION OF PLANT GROWTH REGULATORS AND SEMIPOLAR ORGANIC SOLVENT Stoller Enterprises, Inc. (US) 2023-08-02 EP claimed
EP-3378314-B1 SYNERGISTIC HERBICIDAL COMPOSITION QINGDAO KINGAGROOT RESISTANT WEED MAN CO LTD (CN) 2023-07-05 EP claimed
WO-2023058039-A1 A METHOD FOR CONTROLLING THE GROWTH OF UNDESIRABLE VEGETATION UPL LIMITED (IN) 2023-04-13 WO claimed
CN-115349524-A Herbicidal mixtures 孟山都技术有限公司 2022-11-18 CN claimed
CN-115286499-A Production process of 4-chloro-2-methylphenoxyacetic acid 安徽兴隆化工有限公司 2022-11-04 CN claimed
US-20220033838-A1 BRASSICA EVENT MON94100 AND METHODS OF USE THEREOF MONSANTO TECHNOLOGY LLC (US) 2022-02-03 US claimed
EP-0448723-A1 HERBICIDAL COMPOSITION AND METHOD OF KILLING WEED MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-02 EP claimed
WO-1991009831-A1 PRODRUG ANHYDRIDES OF ASPRIN, INDOMETHACIN AND IBUPROFEN, THEIR PREPARATION, COMPOSITIONS, AND ANTI-INFLAMMATORY METHOD OF USE NOVA PHARMACEUTICAL CORPORATION (US) 1991-07-11 WO claimed
EP-0430325-A1 Process for the preparation of alkylamine salts Akzo Nobel N.V. (NL) 1991-06-05 EP claimed
EP-0371212-A2 Herbicidal aqueous bases microemulsion compositions AMERICAN CYANAMID COMPANY (US) 1990-06-06 EP claimed
EP-0275556-A2 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-27 EP claimed
US-4637830-A ALKANOIC ESTERS OF IOXYNIL AND BROMOXYNIC WITH SALTS OF CHLOROBENZOIC ACID OR CHLOROPHENOXYALKANOIC ACID CIBA-GEIGY CORPORATION (US) 1987-01-20 US claimed
CN-85101131-A Novel phenolic ester mixtures 1987-01-17 CN claimed
EP-0147683-A2 A method for the control of Galium Aparine STAUFFER CHEMICAL COMPANY (US) 1985-07-10 EP claimed
US-4213776-A Herbicidal concentrate containing ketone and amide solvents UNIROYAL LTD. (CA) 1980-07-22 US claimed
US-4170464-A SYNERGISTIC 1,2-DIALKYL-3,5-DIPHENYL PYRAZOLIUM SALT AND A PHENOXYACETIC ACID AMERICAN CYANAMID COMPANY (US) 1979-10-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024500-B2 Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof DDT, CYP3A5, CYP4B1 TSHR 1354/4885HTR2A 1327/4885HTR2C 431/4885
US-12084435-B2 Pyridine ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof PDXK, DDT, PNPO TSHR 1500/4885HTR2A 1906/4885HTR2C 882/4885
US-12239130-B2 Encapsulation of herbicides to reduce crop injury HAGH, HACL2, HDHD5 TSHR 3826/4885HTR2A 423/4885HTR2C 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.