Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025700 | 0.80 | KDM4E (0.47) | CYP3A4SMN1; SMN2MEN1LMNACYP1A2 | |
| SCHEMBL3022280 | 0.73 | KCNH2 (0.46) | SMN1; SMN2MEN1LMNACYP1A2TSHR | |
| SCHEMBL15853564 | 0.71 | HTT (0.44) | S1PR1S1PR3CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL697888 | 0.69 | HTT (0.61) | S1PR1S1PR3CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL13234527 | 0.68 | KDM4E (0.43) | CYP3A4SMN1; SMN2MEN1LMNACYP1A2 | |
| SCHEMBL13234908 | 0.68 | KDM4E (0.43) | CYP3A4SMN1; SMN2MEN1LMNACYP1A2 | |
| SCHEMBL4280433 | 0.68 | NCF1 (0.44) | SMN1; SMN2LMNAPDE4APDE3ANCF1 | |
| SCHEMBL13214422 | 0.67 | KDM4E (0.47) | CYP3A4SMN1; SMN2MEN1LMNACYP1A2 | |
| SCHEMBL6035606 | 0.66 | MEN1 (0.60) | MAPK1SMN1; SMN2MEN1LMNAADRA1A | |
| SCHEMBL4276108 | 0.66 | P2RX7 (0.38) | CYP3A4MAPK1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDACAO UNIVERSIDADE FEDERAL DE SAO CARLOS (BR) | 2010-08-05 | — | — | US | disclosed |
| WO-2008144865-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDAÇÃO UNIVERSIDADE FEDERAL DE SÃO CARLOS (BR) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | PF4, KCNQ1, KCNQ2 | S1PR1 3596/4885S1PR3 3366/4885CYP3A4 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.