SCHEMBL4280433

SCHEMBL4280433

CCOCc1cc(COCC)c2ccccc2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.44
MYC P01106 1/20 0.43
KDM4E B2RXH2 4/20 0.41
PDE4A P27815 2/20 0.40
PDE4B Q07343 2/20 0.40
PDE10A Q9Y233 2/20 0.40
TLR8 Q9NR97 3/20 0.40
TLR7 Q9NYK1 2/20 0.40
HPGD P15428 3/20 0.40
ALDH1A1 P00352 3/20 0.40
GAA P10253 1/20 0.40
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
ELANE P08246 1/20 0.39
NUDT1 P36639 1/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4272930 0.79 ALDH1A1 (0.46) NCF1KDM4EHPGDALDH1A1LMNA
SCHEMBL13168773 0.75 PDE4A (0.42) NCF1KDM4EPDE4APDE4BPDE10A
SCHEMBL4197109 0.75 ALDH1A1 (0.45) NCF1KDM4EPDE4APDE4BPDE10A
SCHEMBL4268808 0.74 CYSLTR1 (0.59) PDE10A
SCHEMBL4272910 0.73 NCF1 (0.35) NCF1MYCKDM4EPDE4APDE10A
SCHEMBL9184895 0.73 KDM4E (0.50) KDM4EHPGDALDH1A1GAAELANE
SCHEMBL12853963 0.72 LOXL2 (0.55) NCF1KDM4EPDE10AALDH1A1LMNA
SCHEMBL3970182 0.72 KDM4E (0.49) KDM4EHPGDALDH1A1GAAELANE
SCHEMBL25523802 0.71 KDM4E (0.50) KDM4EPDE10AHPGDALDH1A1LMNA
SCHEMBL1008581 0.71 TLR7 (0.52) NCF1TLR8TLR7NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed