Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613806 | 0.72 | ERBB2 (0.57) | MAPTEP300CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4351921 | 0.72 | ERBB2 (0.57) | MAPTEP300CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL13636983 | 0.71 | — | — | |
| SCHEMBL482716 | 0.71 | MAOA (0.60) | MAOAMAPTLMNAALDH1A1GAA | |
| SCHEMBL29390564 | 0.71 | MAOA (0.60) | MAOAMAPTLMNAALDH1A1GAA | |
| SCHEMBL4571020 | 0.71 | MAOA (0.60) | MAOAMAPTLMNAALDH1A1GAA | |
| SCHEMBL9505061 | 0.70 | TRPA1 (0.42) | HDAC1ALDH1A1TSHR | |
| SCHEMBL10623284 | 0.68 | LMNA (0.50) | MAOAMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13238427 | 0.67 | MAPT (0.45) | MAPTLMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7432799 | 0.67 | EP300 (0.62) | CISD1MAOAMAOBMAPTEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7758897-B2 | Method for the production of metal complexes | EVONIK OXENO GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-7758897-B2 | Method for the production of metal complexes | EVONIK OXENO GMBH (DE) | 2010-07-20 | — | — | US | disclosed |