Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239488 | 0.85 | ESR1 (0.38) | SMN1; SMN2ALDH1A1ESR1ESR2PTPRB | |
| SCHEMBL12904040 | 0.80 | ESR1 (0.37) | SMN1; SMN2ALDH1A1ESR1ESR2PTPRB | |
| SCHEMBL10329642 | 0.79 | ESR1 (0.34) | SMN1; SMN2ALDH1A1ESR1ESR2PTPRB | |
| SCHEMBL12904053 | 0.78 | PTPRB (0.33) | SMN1; SMN2ALDH1A1ESR1ESR2PTPRB | |
| SCHEMBL10329633 | 0.78 | ESR1 (0.41) | ESR1ESR2PTPRBNPC1PPARG | |
| SCHEMBL12904046 | 0.77 | MEN1 (0.51) | SMN1; SMN2PTPRBTSHRKDM4EMAPK1 | |
| SCHEMBL13239493 | 0.77 | PTPRB (0.46) | ALDH1A1ESR1ESR2PTPRBMEN1 | |
| SCHEMBL12904067 | 0.74 | PTPRB (0.39) | SMN1; SMN2ALDH1A1ESR1ESR2PTPRB | |
| SCHEMBL12904044 | 0.73 | SAE1 (0.43) | SMN1; SMN2ALDH1A1ESR1ESR2PTPRB | |
| SCHEMBL12904068 | 0.73 | PTPRB (0.54) | SMN1; SMN2ALDH1A1PTPRBKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759388-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | SMN1; SMN2 3291/4885ALDH1A1 1647/4885ESR1 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.