Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 16/20 | 0.62 |
| ▸ | ITGB7 | P26010 | 13/20 | 0.62 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10329613 | 0.86 | ITGA4 (0.77) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL29374360 | 0.86 | ITGA4 (0.77) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL10329621 | 0.85 | ITGA4 (0.61) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL12889777 | 0.84 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7538961 | 0.83 | ITGB1 (0.73) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL4066390 | 0.82 | L3MBTL1 (0.69) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL10329617 | 0.81 | ITGB1 (0.70) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL4817521 | 0.81 | ITGA4 (0.75) | ITGA4ITGB1ITGB7 | |
| SCHEMBL18068321 | 0.81 | ITGB1 (0.68) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL4072704 | 0.81 | ITGB1 (0.68) | ITGA4ITGB1ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759388-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7759388-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | ITGA4 3/4885ITGB1 17/4885ITGB7 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.