Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159532 | 0.87 | ALDH1A1 (0.65) | ALDH1A1FFAR1HTTTDP1L3MBTL1 | |
| SCHEMBL22277900 | 0.82 | ALDH1A1 (0.59) | ALDH1A1FFAR1HTTTDP1L3MBTL1 | |
| SCHEMBL9673186 | 0.81 | FFAR1 (0.55) | ALDH1A1FFAR1FDFT1LTA4H | |
| SCHEMBL9889554 | 0.81 | ALDH1A1 (0.67) | ALDH1A1FFAR1HTTTDP1L3MBTL1 | |
| SCHEMBL9889449 | 0.81 | ALDH1A1 (0.57) | ALDH1A1FFAR1HTTTDP1L3MBTL1 | |
| SCHEMBL10013918 | 0.80 | ALDH1A1 (0.65) | ALDH1A1FFAR1HTTTDP1L3MBTL1 | |
| SCHEMBL3309069 | 0.80 | ALDH1A1 (0.45) | ALDH1A1FFAR1HTTTDP1L3MBTL1 | |
| SCHEMBL14159539 | 0.79 | ALDH1A1 (0.80) | ALDH1A1HTTTDP1L3MBTL1ACHE | |
| SCHEMBL10013917 | 0.79 | ALDH1A1 (0.80) | ALDH1A1HTTTDP1L3MBTL1ACHE | |
| SCHEMBL1563176 | 0.79 | FDFT1 (0.38) | ALDH1A1FFAR1HTTFDFT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763752-B2 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | KOHNO YASUSHI | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156653-A1 | Amino alcohol derivatives, salts thereof and immunosuppresive agents | ADH1A, TPMT, AADAT | ALDH1A1 38/4885FFAR1 2145/4885HTT 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.