Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242004 | 0.84 | CES2 (0.40) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL17735845 | 0.84 | CES2 (0.40) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL13242019 | 0.84 | CES2 (0.40) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL13242005 | 0.84 | HSD17B1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL12376989 | 0.84 | MEN1 (0.36) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL5036464 | 0.84 | MEN1 (0.36) | NPC1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL17735830 | 0.83 | CES2 (0.39) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL16938084 | 0.83 | CES2 (0.43) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL17735838 | 0.83 | CES2 (0.43) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL13242011 | 0.81 | MAPT (0.34) | CES2CES1MAPTSMN1; SMN2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481238-B2 | Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20100183332-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20100183332-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |