Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242005 | 0.85 | HSD17B1 (0.43) | NPC1RAB9AHSD17B2HSD17B1SMN1; SMN2 | |
| SCHEMBL13242007 | 0.82 | CES2 (0.45) | RELANFKB1NFKB2HPGDKDM4E | |
| SCHEMBL9777053 | 0.82 | MAPT (0.53) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL17735852 | 0.81 | TSHR (0.44) | NPC1RAB9ALMNAHPGDKDM4E | |
| SCHEMBL21188357 | 0.80 | KDM4E (0.53) | NPC1RAB9ASMN1; SMN2ACHEHPGD | |
| SCHEMBL21188353 | 0.79 | KDM4E (0.49) | NPC1RAB9AHSD17B2HSD17B1SMN1; SMN2 | |
| SCHEMBL13580064 | 0.79 | KDM4E (0.47) | NPC1RAB9ARELANFKB1NFKB2 | |
| SCHEMBL13580063 | 0.77 | CYP3A4 (0.43) | NPC1RAB9AHSD17B2HSD17B1SMN1; SMN2 | |
| SCHEMBL14570731 | 0.76 | ACHE (0.48) | NPC1RAB9ARELATP53NFKB1 | |
| SCHEMBL13152209 | 0.76 | ACHE (0.48) | NPC1RAB9ARELATP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481238-B2 | Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-8481238-B2 | Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20100183332-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20100183332-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |