Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.72 |
| ▸ | CA4 | P22748 | 3/20 | 0.72 |
| ▸ | CA6 | P23280 | 3/20 | 0.72 |
| ▸ | CA5A | P35218 | 3/20 | 0.72 |
| ▸ | CA7 | P43166 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.72 |
| ▸ | MET | P08581 | 11/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318303 | 1.00 | CA12 (0.72) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13242557 | 0.93 | CA12 (0.71) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13242547 | 0.92 | MET (0.70) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13242546 | 0.90 | CA12 (0.58) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13242548 | 0.90 | MET (0.71) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL29009258 | 0.86 | MET (0.86) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL1321817 | 0.85 | MET (0.69) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13242533 | 0.85 | MET (0.69) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13242554 | 0.85 | CA12 (0.69) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL3640072 | 0.85 | CA12 (0.60) | CA12CA4CA6CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179192-A1 | USE OF NITRIC OXIDE RELEASING COMPOUNDS IN THE TREATMENT OF CHRONIC PAIN | NICOX S.A. (FR) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179192-A1 | USE OF NITRIC OXIDE RELEASING COMPOUNDS IN THE TREATMENT OF CHRONIC PAIN | NOS1, NOS2, NOS3 | CA12 3464/4885CA4 2043/4885CA6 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.