Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA3 | P07451 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Nitrophenol SCHEMBL2906482 | 0.86 | CA1 (0.54) | CA1CA2CA9CA5APTGS1 | |
| Trifluoromethanesulfonic Acid SCHEMBL28570941 | 0.85 | CA1 (0.50) | CA1CA2CA9CA5AHSD11B1 | |
| 4-Nitroaniline SCHEMBL28189154 | 0.84 | ALDH1A1 (0.64) | CA1CA2CA9CA5AHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4574955 | 0.84 | CA1 (0.49) | CA1CA2CA9CA5AHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL22389552 | 0.84 | CA1 (0.49) | CA1CA2CA9CA5AHSD11B1 | |
| Nitrobenzene SCHEMBL2888054 | 0.83 | ALDH1A1 (0.61) | CA1CA2CA9CA5AHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL576036 | 0.82 | LMNA (0.52) | CA1CA2CA9CA5APTGS1 | |
| P-Nitrophenol SCHEMBL29806213 | 0.82 | CES1 (0.58) | CA1CA2PTGS1PTGS2CES1 | |
| P-Nitrophenol SCHEMBL11048842 | 0.82 | CES1 (0.58) | CA1CA2PTGS1PTGS2CES1 | |
| P-Nitrophenol SCHEMBL1839 | 0.82 | CES1 (0.58) | CA1CA2PTGS1PTGS2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| CN-102093150-B | Method for synthesizing aromatic amine | BEIJING INST TECHNOLOGY | 2013-10-09 | — | — | CN | disclosed |
| EP-1937689-B1 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDINS SUCH AS ECTEINASCIDINS 583 AND 597 USING SUCH INTERMEDIATE | CENTRE NAT RECH SCIENT (FR) | 2012-04-18 | — | — | EP | disclosed |
| US-8058435-B2 | Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-11-15 | — | — | US | disclosed |
| US-7999090-B2 | reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered; antifungal agents; inhibiting expression of cell wall glycoproteins and preventing pathogens from showing pathogenicity; DNA | EISAI CO., LTD (JP) | 2011-08-16 | — | — | US | disclosed |
| CN-102093150-A | Method for synthesizing aromatic amine | BEIJING INST TECHNOLOGY | 2011-06-15 | — | — | CN | disclosed |
| US-7928209-B2 | reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered; antifungal agents; inhibiting expression of cell wall glycoproteins and preventing pathogens from showing pathogenicity; DNA | EISAI R & D MANAGEMENT CO. LTD. (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7910712-B2 | Fungal cell wall synthesis gene | EISAI R&D MANAGEMENT CO., LTD (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7375204-B2 | Fungal cell wall synthesis gene | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |
| EP-1792904-A1 | Intermediate and process of preparation of ecteinascidin using such intermediate | Centre National de la Recherche Scientifique (CNRS) (FR) | 2007-06-06 | — | — | EP | disclosed |
| CN-1873002-A | Fungal cell wall synthesis gene | EISAI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1873003-A | Fungal cell wall synthesis gene | EISAI CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| US-20060234283-A1 | Fungal cell wall synthesis gene | EISAI CO., LTD. (JP) | 2006-10-19 | — | — | US | disclosed |
| US-20060234349-A1 | Fungal cell wall synthesis gene | EISAI CO., LTD. (JP) | 2006-10-19 | — | — | US | disclosed |
| CN-1249227-C | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2006-04-05 | — | — | CN | disclosed |
| US-20040038239-A1 | Fungal cell wall synthesis gene | EISAI CO., LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
| CN-1449443-A | Fungal cell wall synthetic genes | EISAI CO LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| EP-1300464-A1 | FUNGAL CELL WALL SYNTHESIS GENE | Eisai Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038239-A1 | Fungal cell wall synthesis gene | ERG28, GPI, DPM1 | CA1 4497/4885CA2 3944/4885CA9 3394/4885 |
| US-20060234349-A1 | Fungal cell wall synthesis gene | ERG28, GPI, DPM1 | CA1 4497/4885CA2 3944/4885CA9 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.