SCHEMBL132448

SCHEMBL132448

O=S(=O)(O)c1ccccc1.[KH]

nearest known ligand 0.94

Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.94
SMN1; SMN2 Q16637 1/20 0.94
POLB P06746 1/20 0.60
CYP2D6 P10635 1/20 0.60
HTR6 P50406 1/20 0.55
LMNA P02545 1/20 0.55
ALDH1A1 P00352 4/20 0.52
NT5E P21589 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
HSD17B10 Q99714 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
PLA2G7 Q13093 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2243698 1.00 TSHR (0.94) TSHRSMN1; SMN2POLBCYP2D6HTR6
Hydrogen Peroxide SCHEMBL28250789 1.00 TSHR (0.94) TSHRSMN1; SMN2POLBCYP2D6HTR6
SCHEMBL27416173 1.00 TSHR (0.94) TSHRSMN1; SMN2POLBCYP2D6HTR6
SCHEMBL28218944 0.97 TSHR (0.89) TSHRSMN1; SMN2POLBCYP2D6HTR6
Ammonia Solution, Strong SCHEMBL11068107 0.97 TSHR (0.89) TSHRSMN1; SMN2POLBCYP2D6HTR6
Water SCHEMBL27709309 0.97 TSHR (0.89) TSHRSMN1; SMN2POLBCYP2D6HTR6
SCHEMBL29056347 0.97 TSHR (0.89) TSHRSMN1; SMN2POLBCYP2D6HTR6
Bromide SCHEMBL8154558 0.97 TSHR (0.89) TSHRSMN1; SMN2POLBCYP2D6HTR6
Water SCHEMBL28070633 0.97 TSHR (0.89) TSHRSMN1; SMN2POLBCYP2D6HTR6
Benzene SCHEMBL9751882 0.97 TSHR (1.00) TSHRSMN1; SMN2POLBCYP2D6HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 805 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255615-B1 POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM SYENSQO SPECIALTY POLYMERS USA LLC (US) 2026-04-22 EP claimed
CN-119280450-A Medical fabric dressing with long-acting disinfection and sterilization functions and preparation method thereof 孙国明 2025-01-10 CN claimed
CN-118844836-A Long-acting disinfection and sterilization wet (towel) paper 孙国明 2024-10-29 CN claimed
CN-118844448-A Preparation method of long-acting antibacterial liquid 孙国明 2024-10-29 CN claimed
CN-116410727-B Dilution thickening type surfactant spherical micelle super-concentrated dispersion system, and preparation method and application thereof 武汉大学 2024-09-27 CN claimed
CN-114621059-B Method for producing m-diphenol by neutralizing alkali molten material with sulfonated material 山东创蓝垚石环保技术有限公司 2024-07-02 CN claimed
CN-117623420-A Water treatment agent and water treatment method for steam-water-free cyclone separator boiler 广东中南钢铁股份有限公司 2024-03-01 CN claimed
US-20240017219-A1 POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2024-01-18 US claimed
EP-4255615-A1 POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM Solvay Specialty Polymers USA, LLC (US) 2023-10-11 EP claimed
CN-116761667-A Polymer composition and method for producing film therefrom 索尔维特殊聚合物美国有限责任公司 2023-09-15 CN claimed
CN-1387506-A Preparation of aryl carboxylates EASTMAN CHEM CO (US) 2002-12-25 CN claimed
CN-1288003-A Method for prepn. of aryl carboxylic ester EASTMAN CHEM CO (US) 2001-03-21 CN claimed
CN-1233391-A Preservation liquid for animal body specimen NEW TECH DEV CO BEIJING YANSHA (CN) 1999-11-03 CN claimed
EP-0524427-A2 Aqueous hair styling aid HELENE CURTIS, INC. (US) 1993-01-27 EP claimed
US-5164177-A Aqueous aerosol or nonaerosol hair spray HELENE CURTIS, INC. (US) 1992-11-17 US claimed
CN-1030769-A The improvement of hexafluoropropylene (HFP)/tetrafluoroethylene (TFE) copolymerization process SHANGHAI INST OF ORGANO FLUORO (CN) 1989-02-01 CN claimed
EP-0021769-B1 PROCESSES FOR PRODUCING 2,6-DIMETHYL-3-ALKOXY-OCT-1-EN-8-OL, DEHYDROCITRONELLOL AND 2-(2'-METHYL-1'-PROPENYL)-4-METHYLTETRAHYDROPYRAN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-09 EP claimed
US-4312717-A ANODIC ALKOXYLATION OF CITRONELLOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-01-26 US claimed
EP-0021769-A1 Processes for producing 2,6-dimethyl-3-alkoxy-oct-1-en-8-ol, dehydrocitronellol and 2-(2'-methyl-1'-propenyl)-4-Methyltetrahydropyran SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-07 EP claimed
US-4104253-A HALOGENATED ORGANIC ALKALI OR ALKALINE EARTH METAL SALTS GENERAL ELECTRIC COMPANY (US) 1978-08-01 US claimed