Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022799 | 1.00 | GPR139 (0.39) | GPR139 | |
| SCHEMBL3022803 | 1.00 | GPR139 (0.39) | GPR139 | |
| SCHEMBL3018329 | 0.91 | OPRK1 (0.40) | GPR139 | |
| SCHEMBL3018325 | 0.91 | OPRK1 (0.40) | GPR139 | |
| SCHEMBL3018332 | 0.91 | OPRK1 (0.40) | GPR139 | |
| SCHEMBL13984712 | 0.89 | GPR139 (0.44) | GPR139 | |
| SCHEMBL404266 | 0.89 | GPR139 (0.44) | GPR139 | |
| SCHEMBL15382520 | 0.89 | GPR139 (0.44) | GPR139 | |
| SCHEMBL13245500 | 0.89 | GPR139 (0.44) | GPR139 | |
| SCHEMBL13267396 | 0.88 | GPR139 (0.45) | GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | GPR139 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.