SCHEMBL1324546

SCHEMBL1324546

CC(Cc1cc(Br)c(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.42
TSHR P16473 3/20 0.39
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ALOX15 P16050 3/20 0.38
ALOX12 P18054 3/20 0.38
HSD17B10 Q99714 3/20 0.38
HIF1A Q16665 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
PTPN1 P18031 1/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2D6 P10635 1/20 0.35
FOLH1 Q04609 1/20 0.34
TTR P02766 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901082 0.91 ADRB2 (0.38) ESR1ESR2TSHRCYP3A4TDP1
SCHEMBL1956103 0.91 ADRB2 (0.38) ESR1ESR2TSHRCYP3A4TDP1
SCHEMBL27981343 0.91 ADRB2 (0.38) ESR1ESR2TSHRCYP3A4TDP1
SCHEMBL27981742 0.87 PTPN1 (0.41) ESR1ESR2TSHRHSD17B10HIF1A
SCHEMBL901085 0.87 PTPN1 (0.41) ESR1ESR2TSHRHSD17B10HIF1A
SCHEMBL582053 0.85 ESR1 (0.42) ESR1ESR2TSHRCYP3A4TDP1
SCHEMBL13920802 0.79 ALDH1A1 (0.44) ESR1TSHRCYP3A4TDP1ALOX15
SCHEMBL9808125 0.76 FOLH1 (0.40) ESR1TSHRCYP3A4TDP1ALOX15
SCHEMBL12631075 0.76 TSHR (0.39) ESR1TSHRCYP3A4TDP1ALOX15
SCHEMBL5474836 0.73 ESR1 (0.44) ESR1ESR2CYP3A4TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US claimed
US-20210019584-A1 A LASER MARKABLE RFID TAG AGFA NV (BE) 2021-01-21 US disclosed
US-10853712-B2 Authentication method of a two dimensional bar code AGFA NV (BE) 2020-12-01 US disclosed
US-10767063-B2 Aqueous inkjet inks AGFA-GEVAERT NV (BE) 2020-09-08 US disclosed
US-20190351691-A1 A MULTICOLOUR LASER MARKING METHOD AGFA-GEVAERT NV (BE) 2019-11-21 US disclosed
EP-3095825-B1 AQUEOUS INKJET INKS AGFA GEVAERT NV (BE) 2019-10-02 EP disclosed
EP-3297838-B1 LASER MARKABLE MATERIALS AND DOCUMENTS AGFA GEVAERT (BE) 2019-08-28 EP disclosed
EP-3297837-B1 LASER MARKABLE COMPOSITIONS, ARTICLES AND DOCUMENTS AGFA GEVAERT (BE) 2019-07-31 EP disclosed
US-10286707-B2 Laser markable compositions, materials and documents AGFA-GEVAERT (BE) 2019-05-14 US disclosed
US-10286708-B2 Laser markable compositions, articles and documents AGFA-GEVAERT (BE) 2019-05-14 US disclosed
US-8268746-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-09-18 US disclosed
EP-2230090-B1 Method and apparatus for producing thermosensitive recording material RICOH CO LTD (JP) 2012-08-29 EP disclosed
US-8058209-B2 Leuco dyes and developers; protective layers, development layers formed by curtain coating RICOH COMPANY, LTD. (JP) 2011-11-15 US disclosed
US-20100239766-A1 Method And Apparatus For Producing Thermosensitive Recording Material RICOH COMPANY, LTD. (JP) 2010-09-23 US disclosed
EP-2230090-A1 Method and apparatus for producing thermosensitive recording material Ricoh Company, Ltd. (JP) 2010-09-22 EP disclosed
EP-2163393-A1 Thermosensitive recording material Ricoh Co., Ltd. (JP) 2010-03-17 EP disclosed
US-20100062936-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2010-03-11 US disclosed
EP-1972459-B1 Heat-sensitive recording material RICOH KK (JP) 2009-11-04 EP disclosed
US-20080234128-A1 HEAT-SENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2008-09-25 US disclosed
EP-1972459-A1 Heat-sensitive recording material Ricoh Company, Ltd. (JP) 2008-09-24 EP disclosed