Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981343 | 1.00 | ADRB2 (0.38) | ADRB2ESR1ESR2CYP3A4TSHR | |
| SCHEMBL901082 | 1.00 | ADRB2 (0.38) | ADRB2ESR1ESR2CYP3A4TSHR | |
| SCHEMBL1324546 | 0.91 | ESR1 (0.42) | ESR1ESR2CYP3A4TSHRTDP1 | |
| SCHEMBL900506 | 0.81 | GSK3B (0.36) | ADRB2ESR1TSHRGSK3BTHRA | |
| SCHEMBL901085 | 0.80 | PTPN1 (0.41) | ESR1ESR2TSHRHSD17B10HIF1A | |
| SCHEMBL27981742 | 0.80 | PTPN1 (0.41) | ESR1ESR2TSHRHSD17B10HIF1A | |
| SCHEMBL582053 | 0.78 | ESR1 (0.42) | ADRB2ESR1ESR2CYP3A4TSHR | |
| SCHEMBL14990488 | 0.77 | ESR1 (0.33) | ADRB2ESR1ESR2GAAMAPT | |
| SCHEMBL13920802 | 0.72 | ALDH1A1 (0.44) | ESR1CYP3A4TSHRTDP1GAA | |
| SCHEMBL12631075 | 0.69 | TSHR (0.39) | ESR1CYP3A4TSHRTDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726529-A1 | HYBRID EPOXY RESINS | Dow Global Technologies LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| US-8680217-B2 | Polycyclopentadiene compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-03-25 | — | — | US | disclosed |
| WO-2013055411-A1 | HYBRID EPOXY RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-18 | — | — | WO | disclosed |
| US-20130046067-A1 | POLYCYCLOPENTADIENE COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-21 | — | — | US | disclosed |
| EP-2507325-A1 | COATING COMPOSITIONS | Dow Global Technologies LLC (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-2507283-A1 | EPOXY RESIN COMPOSITIONS | Dow Global Technologies LLC (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068645-A1 | COATING COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011068644-A1 | EPOXY RESIN COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046067-A1 | POLYCYCLOPENTADIENE COMPOUNDS | ERCC1, ERCC5, ERCC2 | ADRB2 4634/4885ESR1 559/4885ESR2 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.