Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PCK1 | P35558 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268061 | 0.89 | ADORA1 (0.47) | ADORA1ADORA2AEPHX1PCK1 | |
| SCHEMBL3115385 | 0.87 | ADORA1 (0.49) | ADORA1ADORA2A | |
| SCHEMBL13247654 | 0.84 | ADORA1 (0.53) | ADORA1ADORA2A | |
| SCHEMBL3118810 | 0.84 | ADORA1 (0.46) | ADORA1ADORA2A | |
| SCHEMBL3114323 | 0.83 | ADORA1 (0.48) | ADORA1ADORA2A | |
| SCHEMBL3114352 | 0.83 | ADORA1 (0.47) | ADORA1ADORA2A | |
| SCHEMBL13247897 | 0.83 | ADORA1 (0.50) | ADORA1ADORA2A | |
| Trifluoroacetic Acid SCHEMBL3119762 | 0.82 | ADORA1 (0.43) | ADORA1ADORA2A | |
| SCHEMBL3119443 | 0.81 | SIRT1 (0.54) | ADORA1ADORA2A | |
| SCHEMBL3117068 | 0.80 | ADORA1 (0.52) | ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | XDH, GPR84, GPR88 | ADORA1 32/4885ADORA2A 17/4885EPHX1 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.