Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45984 | 1.00 | OPRD1 (0.35) | OPRD1OPRM1OPRK1HCRTR1TMEM97 | |
| SCHEMBL46005 | 0.89 | — | — | |
| SCHEMBL46013 | 0.89 | OPRD1 (0.32) | OPRD1OPRM1OPRK1 | |
| SCHEMBL10072374 | 0.88 | HCRTR1 (0.42) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL10072368 | 0.87 | OPRM1 (0.33) | OPRD1OPRM1OPRK1HCRTR1TMEM97 | |
| SCHEMBL13660037 | 0.85 | OPRM1 (0.35) | OPRD1OPRM1OPRK1HCRTR1 | |
| SCHEMBL13248813 | 0.83 | — | — | |
| SCHEMBL46009 | 0.80 | HCRTR1 (0.30) | HCRTR1 | |
| SCHEMBL13963260 | 0.80 | — | — | |
| SCHEMBL13248811 | 0.78 | OPRD1 (0.32) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197921-A1 | Preparation of N-Alkylated Opiates by Reductive Amination | MALLINCKRODT ENTERPRISES LLC | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197921-A1 | Preparation of N-Alkylated Opiates by Reductive Amination | OPRM1, OPRD1, OPRK1 | OPRD1 2/4885OPRM1 1/4885OPRK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.