Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46009 | 0.92 | HCRTR1 (0.30) | — | |
| SCHEMBL13248804 | 0.89 | OPRD1 (0.35) | OPRD1OPRM1OPRK1 | |
| SCHEMBL45984 | 0.89 | OPRD1 (0.35) | OPRD1OPRM1OPRK1 | |
| SCHEMBL46005 | 0.85 | — | — | |
| SCHEMBL13963260 | 0.82 | — | — | |
| SCHEMBL14161022 | 0.80 | HCRTR1 (0.37) | OPRD1OPRM1OPRK1 | |
| SCHEMBL18473427 | 0.80 | HCRTR1 (0.37) | OPRD1OPRM1OPRK1 | |
| SCHEMBL13248813 | 0.80 | — | — | |
| SCHEMBL13962904 | 0.79 | OPRM1 (0.37) | OPRD1OPRM1OPRK1 | |
| SCHEMBL13847996 | 0.79 | OPRM1 (0.36) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005795-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED MORPHINANS | ALKERMES, INC. (US) | 2012-01-12 | — | — | WO | disclosed |