Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798421 | 0.94 | GBA1 (0.41) | GBA1EPHX2FDFT1NPSR1 | |
| SCHEMBL19798414 | 0.85 | FDFT1 (0.40) | GBA1EPHX2FDFT1 | |
| SCHEMBL19798747 | 0.77 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL19798406 | 0.76 | FDFT1 (0.35) | FDFT1 | |
| SCHEMBL92309 | 0.75 | FDFT1 (0.35) | EPHX2FDFT1ALDH1A1 | |
| SCHEMBL19798422 | 0.74 | FDFT1 (0.39) | FDFT1CNR2 | |
| SCHEMBL16566372 | 0.71 | FDFT1 (0.36) | FDFT1ALDH1A1 | |
| SCHEMBL29226312 | 0.71 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL19798413 | 0.71 | FDFT1 (0.37) | FDFT1NPSR1ALDH1A1 | |
| SCHEMBL5164652 | 0.71 | GBA1 (0.39) | GBA1EPHX2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318355-B1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-8309597-B2 | 1,1′-diadamantyl carboxylic acids, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20110269736-A1 | 1,1'-Diadamantyl carboxylic acids, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2011-11-03 | — | — | US | disclosed |
| EP-2318355-A1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | Boehringer Ingelheim International GmbH (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010010174-A1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269736-A1 | 1,1'-Diadamantyl carboxylic acids, medicaments containing such compounds and their use | HSD11B1, HSD17B1, HSD3B1 | GBA1 519/4885EPHX2 1205/4885FDFT1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.