Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.46 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761764 | 0.92 | DGAT1 (0.46) | DGAT1CSGALNACT1DHODHCFTRPTGDR2 | |
| SCHEMBL1762132 | 0.92 | DGAT1 (0.47) | DGAT1CSGALNACT1DHODHCFTRPTGDR2 | |
| SCHEMBL1761762 | 0.90 | DGAT1 (0.47) | DGAT1CSGALNACT1GRNSORT1DHODH | |
| Trifluoroacetic Acid SCHEMBL1761834 | 0.90 | DGAT1 (0.44) | DGAT1CSGALNACT1DHODHCFTRPTGDR2 | |
| Trifluoroacetic Acid SCHEMBL1761467 | 0.89 | DGAT1 (0.45) | DGAT1CSGALNACT1DHODHCFTRPTGDR2 | |
| Trifluoroacetic Acid SCHEMBL1761830 | 0.88 | DGAT1 (0.46) | DGAT1CSGALNACT1GRNSORT1DHODH | |
| SCHEMBL1761941 | 0.87 | DGAT1 (0.49) | DGAT1CSGALNACT1DHODHCFTRPTGDR2 | |
| SCHEMBL1761697 | 0.87 | DGAT1 (0.42) | DGAT1CSGALNACT1GRNSORT1DHODH | |
| Trifluoroacetic Acid SCHEMBL1761405 | 0.85 | DGAT1 (0.47) | DGAT1CSGALNACT1DHODHCFTRPTGDR2 | |
| Trifluoroacetic Acid SCHEMBL1761527 | 0.85 | DGAT1 (0.41) | DGAT1CSGALNACT1GRNSORT1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759376-B2 | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759376-B2 | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, PGC | DGAT1 486/4885CSGALNACT1 3157/4885GRN 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.