Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.54 |
| ▸ | CSGALNACT1 | Q8TDX6 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761753 | 1.00 | DGAT1 (0.54) | DGAT1CSGALNACT1CA2CA1 | |
| Trifluoroacetic Acid SCHEMBL1761464 | 0.96 | DGAT1 (0.51) | DGAT1CSGALNACT1CA2CA1 | |
| SCHEMBL1761469 | 0.88 | DGAT1 (0.42) | DGAT1CSGALNACT1 | |
| SCHEMBL12648638 | 0.87 | DGAT1 (0.40) | DGAT1CSGALNACT1 | |
| SCHEMBL1762153 | 0.84 | DGAT1 (0.59) | DGAT1CSGALNACT1 | |
| SCHEMBL1761395 | 0.84 | DGAT1 (0.67) | DGAT1CSGALNACT1 | |
| SCHEMBL1761366 | 0.82 | DGAT1 (0.80) | DGAT1CSGALNACT1 | |
| Trifluoroacetic Acid SCHEMBL1761434 | 0.80 | DGAT1 (0.55) | DGAT1CSGALNACT1 | |
| SCHEMBL1761936 | 0.80 | DGAT1 (0.55) | DGAT1CSGALNACT1 | |
| SCHEMBL1761585 | 0.80 | DGAT1 (0.67) | DGAT1CSGALNACT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759376-B2 | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265298-A1 | Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, PGC | DGAT1 486/4885CSGALNACT1 3157/4885CA2 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.